Repurposing of antidepression drug sertraline for antimicrobial activity against Staphylococcus aureus : a potential approach for the treatment of osteomyelitis

Osteomyelitis treatment is one of the most challenging issues in orthopedics, which is developed primarily by antibiotic resistant micro organisms. An efficient approach to overcome this issue is repurposing existing drug molecules to combine with the bioactive materials for making local drug delive...

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Veröffentlicht in:	New journal of chemistry 2019, Vol.43 (14), p.5315-5324
Hauptverfasser:	Muthu, D., Gowri, M., Suresh Kumar, G., Kattimani, V. S., Girija, E. K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics Antidepressants Biocompatibility Biofilms Biological activity Chemical activity Chemical analysis Chemical precipitation Drug delivery systems Hydroxyapatite Organic chemistry Orthopedics
Online-Zugang:	Volltext
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