Fluorescence-enhanced p19 proteins-conjugated single quantum dot with multiplex antenna for one-step, specific and sensitive miRNAs detection

Ideal methods for miRNA detection should be rapid and amplification-free in the mix-and-measure format. Here we report a novel FRET strategy based on fluorescence-enhanced p19 proteins-conjugated single quantum dot (QD) with multiplex antenna for one-step, specific and sensitive miRNAs quantitative...

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Veröffentlicht in:	Analytica chimica acta 2019-04, Vol.1053, p.114-121
Hauptverfasser:	Ren, Xueting, Xue, Qingwang, Wen, Liyuan, Li, Xia, Wang, Huaisheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Amplification Antennas Base Sequence Biosensing Techniques - methods Breast cancer Cell Line, Tumor Conjugates Deoxyribonucleic acid DNA Double-stranded RNA Feasibility Studies Fluorescence Fluorescence Resonance Energy Transfer FRET Homogeneous assay Humans Hybridization Limit of Detection MicroRNAs - analysis MicroRNAs - chemistry MicroRNAs - genetics miRNA MiRNA-21 Multiplexing P19 protein Proteins Quantitative analysis Quantum dot (QD) Quantum dots Quantum Dots - chemistry Reagents Ribonucleic acid RNA Selectivity Sensitivity Strategy Target detection Viral Proteins - chemistry
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