Characterization of In vitro Inhibitory Effects of Consensus Short Interference RNAs against Non-Structural 5B Gene of Hepatitis C Virus 1a Genotype

Purpose: Chronic hepatitis C has infected approximately 170 million people worldwide. The novel direct-acting antivirals have proven their clinical efficacy to treat hepatitis C infection but still very expensive and beyond the financial range of most infected patients in low income and even resourc...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Indian journal of medical microbiology 2018-10, Vol.36 (4), p.494-503
Hauptverfasser:	Shahid, Imran, Almalki, Waleed Hassan, Ibrahim, Munjed M., Alghamdi, Sultan Ahmad, Mukhtar, Mohammed H., Almalki, Shaia Saleh R., Alkahtani, Saad Ahmed, Alhaidari, Mohammad S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiviral agents Antiviral Agents - metabolism Cell culture Cell Line Cloning Cytoplasm Deoxyribonucleic acid DNA Drug resistance Drug screening Enzymes Gene Expression Genomes Genotype Genotype & phenotype Genotypes Gentamicin Hepacivirus - classification Hepacivirus - enzymology Hepacivirus - genetics Hepatitis Hepatitis C Hepatitis C virus Hepatocytes - drug effects Hepatoma Humans In vitro methods and tests Infections Interference Liver cancer non-structural 5B protein NS5B protein Nucleotide sequence Pathogenesis Polymerase chain reaction Proteins real-time polymerase chain reaction Replication Reverse transcription Ribonucleic acid RNA RNA Interference RNA polymerase RNA, Small Interfering - metabolism RNA-mediated interference siRNA stable human hepatoma-7 cells Studies Viral infections Viral Nonstructural Proteins - antagonists & inhibitors Viral Nonstructural Proteins - biosynthesis Viruses
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!