Pattern of recurrence following local chemotherapy with biodegradable carmustine (BCNU) implants in patients with glioblastoma

Recently a randomized placebo-controlled phase III trial of biodegradable polymers containing carmustine has demonstrated a significant survival benefit for patients treated with local chemotherapy. A local chemotherapy applied directly to the resection cavity may act directly on residual tumor cell...

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Veröffentlicht in:	Journal of neuro-oncology 2004-02, Vol.66 (3), p.351-360
Hauptverfasser:	GIESE, Alf, KUCINSKI, Thomas, KNOPP, Ulrich, GOLDBRUNNER, Roland, HAMEL, Wolfgang, MEBDORN, H. M, TONN, Jörg C, HILT, Dana, WESTPHAL, Manfred
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorbable Implants Adolescent Adult Age Distribution Aged Antineoplastic Agents, Alkylating - therapeutic use Biological and medical sciences Brain Neoplasms - drug therapy Brain Neoplasms - pathology Carmustine - therapeutic use Drug Implants Glioblastoma - drug therapy Glioblastoma - pathology Humans Medical sciences Middle Aged Neoplasm Recurrence, Local - pathology Neurology Prospective Studies Randomized Controlled Trials as Topic Survival Rate
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