Outcome of renal allografts from non-heart-beating donors with delayed graft function

Outcome of renal allografts from non-heart-beating donors with delayed graft function

Delayed graft function (DGF) in renal transplantation using non-heart-beating donors (NHBDs) usually exceeds 80%. There is debate whether DGF in this subgroup is associated with poor long-term outcome. Between 1 January1988 and 31 January 2000, 130 of 158 (82.3%) NHBD graft recipients with functioni...

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Veröffentlicht in:Transplant international 2002-12, Vol.15 (12), p.660
Hauptverfasser: Gerstenkorn, Clemens, Deardon, David, Koffman, Geoffrey C, Papalois, Vassilios E, Andrews, Peter A
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container_issue 12
container_start_page 660
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creator Gerstenkorn, Clemens
Deardon, David
Koffman, Geoffrey C
Papalois, Vassilios E
Andrews, Peter A
description Delayed graft function (DGF) in renal transplantation using non-heart-beating donors (NHBDs) usually exceeds 80%. There is debate whether DGF in this subgroup is associated with poor long-term outcome. Between 1 January1988 and 31 January 2000, 130 of 158 (82.3%) NHBD graft recipients with functioning grafts transplanted within our regional NHBD programme developed DGF. Overall graft survival and graft survival censored for recipient death was 113/130 (86.9%) versus 113/121 (93.4%) at year 1, 55/84 (65.5%) versus 55/64 (85.9%) at year 5 and 18/40 (45.0%) versus 18/28 (64.3%) at year 10 after transplantation. Seventeen grafts (13.1%) were lost due to rejection or graft nephropathy. Nine of these kidneys failed during the 1st year. Twenty-seven patients (20.8%) died with functioning grafts, eight within the 1st year after transplantation. In those patients who survived, DGF was associated with excellent long-term outcome in this study. The number of grafts lost due to recipient death exceeded those lost due to rejection or graft nephropathy.
doi_str_mv 10.1007/s00147-002-0471-4
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title Outcome of renal allografts from non-heart-beating donors with delayed graft function
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