On the upper limit for the energy of epithermal neutrons for Boron Neutron Capture Therapy
The upper limit of the energy for epithermal neutrons is usually fixed to 10 keV based on the experience with spectra from reactors used until now for Boron Neutron Capture Therapy. The future use of accelerators with this therapy will provide different neutron spectra that require a more detailed s...
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| Veröffentlicht in: | Radiation physics and chemistry (Oxford, England : 1993) England : 1993), 2019-03, Vol.156, p.240-244 |
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| container_title | Radiation physics and chemistry (Oxford, England : 1993) |
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| creator | Torres-Sánchez, P. Porras, I. de Saavedra, F. Arias Sabariego, M.P. Praena, J. |
| description | The upper limit of the energy for epithermal neutrons is usually fixed to 10 keV based on the experience with spectra from reactors used until now for Boron Neutron Capture Therapy. The future use of accelerators with this therapy will provide different neutron spectra that require a more detailed study of this upper limit. Using our own Monte Carlo neutron transport code, we have calculated figures of merit on the dose depth profile to find this upper limit. Our results indicate that this upper limit could be incremented up to 15–20 keV under these new conditions.
•An increase of the upper limit of the energy of epithermal neutrons for BNCT has been proposed.•A fast computer code for evaluating dose depth profiles for BNCT has been introduced.•Useful analytical parametrizations of the different dose components for a standard tissue have been obtained.•Figures of merit for different neutron energies have been calculated and their dependence on the energy has been discussed. |
| doi_str_mv | 10.1016/j.radphyschem.2018.11.015 |
| format | Article |
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•An increase of the upper limit of the energy of epithermal neutrons for BNCT has been proposed.•A fast computer code for evaluating dose depth profiles for BNCT has been introduced.•Useful analytical parametrizations of the different dose components for a standard tissue have been obtained.•Figures of merit for different neutron energies have been calculated and their dependence on the energy has been discussed.</description><identifier>ISSN: 0969-806X</identifier><identifier>EISSN: 1879-0895</identifier><identifier>DOI: 10.1016/j.radphyschem.2018.11.015</identifier><language>eng</language><publisher>Oxford: Elsevier Ltd</publisher><subject>Accelerators ; BNCT ; Boron ; Dose depth profile ; Fast neutrons ; Monte Carlo simulations ; Neutron spectra ; Neutrons ; Nuclear capture ; Therapy</subject><ispartof>Radiation physics and chemistry (Oxford, England : 1993), 2019-03, Vol.156, p.240-244</ispartof><rights>2018 Elsevier Ltd</rights><rights>Copyright Elsevier BV Mar 2019</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c349t-55fb26834e2e31ee5ad0b625d54fc03f2ca403259c26784974d3199e42b4fdcd3</citedby><cites>FETCH-LOGICAL-c349t-55fb26834e2e31ee5ad0b625d54fc03f2ca403259c26784974d3199e42b4fdcd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.radphyschem.2018.11.015$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,778,782,3539,27907,27908,45978</link.rule.ids></links><search><creatorcontrib>Torres-Sánchez, P.</creatorcontrib><creatorcontrib>Porras, I.</creatorcontrib><creatorcontrib>de Saavedra, F. Arias</creatorcontrib><creatorcontrib>Sabariego, M.P.</creatorcontrib><creatorcontrib>Praena, J.</creatorcontrib><title>On the upper limit for the energy of epithermal neutrons for Boron Neutron Capture Therapy</title><title>Radiation physics and chemistry (Oxford, England : 1993)</title><description>The upper limit of the energy for epithermal neutrons is usually fixed to 10 keV based on the experience with spectra from reactors used until now for Boron Neutron Capture Therapy. The future use of accelerators with this therapy will provide different neutron spectra that require a more detailed study of this upper limit. Using our own Monte Carlo neutron transport code, we have calculated figures of merit on the dose depth profile to find this upper limit. Our results indicate that this upper limit could be incremented up to 15–20 keV under these new conditions.
•An increase of the upper limit of the energy of epithermal neutrons for BNCT has been proposed.•A fast computer code for evaluating dose depth profiles for BNCT has been introduced.•Useful analytical parametrizations of the different dose components for a standard tissue have been obtained.•Figures of merit for different neutron energies have been calculated and their dependence on the energy has been discussed.</description><subject>Accelerators</subject><subject>BNCT</subject><subject>Boron</subject><subject>Dose depth profile</subject><subject>Fast neutrons</subject><subject>Monte Carlo simulations</subject><subject>Neutron spectra</subject><subject>Neutrons</subject><subject>Nuclear capture</subject><subject>Therapy</subject><issn>0969-806X</issn><issn>1879-0895</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNqNkE9LxDAQxYMouK5-h4jn1iRN2uaoxX-wuJcVxEvIplM3ZdvUpBX67e1uPXj0NMPj994wD6FrSmJKaHpbx16X3W4MZgdNzAjNY0pjQsUJWtA8kxHJpThFCyJTGeUkfT9HFyHUhJAsF8kCfaxb3O8AD10HHu9tY3tcOX_UoAX_OWJXYejsJPhG73ELQ-9dG47UvZtW_DpLuNBdP3jAmwnV3XiJziq9D3D1O5fo7fFhUzxHq_XTS3G3ikzCZR8JUW1ZmiccGCQUQOiSbFMmSsErQ5KKGc1JwoQ0LM1yLjNeJlRK4GzLq9KUyRLdzLmdd18DhF7VbvDtdFIxKgXjGRN0ouRMGe9C8FCpzttG-1FRog5Vqlr9qVIdqlSUqqnKyVvMXpje-LbgVTAWWgOl9WB6VTr7j5QfY0GDmg</recordid><startdate>201903</startdate><enddate>201903</enddate><creator>Torres-Sánchez, P.</creator><creator>Porras, I.</creator><creator>de Saavedra, F. Arias</creator><creator>Sabariego, M.P.</creator><creator>Praena, J.</creator><general>Elsevier Ltd</general><general>Elsevier BV</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>L7M</scope></search><sort><creationdate>201903</creationdate><title>On the upper limit for the energy of epithermal neutrons for Boron Neutron Capture Therapy</title><author>Torres-Sánchez, P. ; Porras, I. ; de Saavedra, F. Arias ; Sabariego, M.P. ; Praena, J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c349t-55fb26834e2e31ee5ad0b625d54fc03f2ca403259c26784974d3199e42b4fdcd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Accelerators</topic><topic>BNCT</topic><topic>Boron</topic><topic>Dose depth profile</topic><topic>Fast neutrons</topic><topic>Monte Carlo simulations</topic><topic>Neutron spectra</topic><topic>Neutrons</topic><topic>Nuclear capture</topic><topic>Therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Torres-Sánchez, P.</creatorcontrib><creatorcontrib>Porras, I.</creatorcontrib><creatorcontrib>de Saavedra, F. Arias</creatorcontrib><creatorcontrib>Sabariego, M.P.</creatorcontrib><creatorcontrib>Praena, J.</creatorcontrib><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Radiation physics and chemistry (Oxford, England : 1993)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Torres-Sánchez, P.</au><au>Porras, I.</au><au>de Saavedra, F. Arias</au><au>Sabariego, M.P.</au><au>Praena, J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>On the upper limit for the energy of epithermal neutrons for Boron Neutron Capture Therapy</atitle><jtitle>Radiation physics and chemistry (Oxford, England : 1993)</jtitle><date>2019-03</date><risdate>2019</risdate><volume>156</volume><spage>240</spage><epage>244</epage><pages>240-244</pages><issn>0969-806X</issn><eissn>1879-0895</eissn><abstract>The upper limit of the energy for epithermal neutrons is usually fixed to 10 keV based on the experience with spectra from reactors used until now for Boron Neutron Capture Therapy. The future use of accelerators with this therapy will provide different neutron spectra that require a more detailed study of this upper limit. Using our own Monte Carlo neutron transport code, we have calculated figures of merit on the dose depth profile to find this upper limit. Our results indicate that this upper limit could be incremented up to 15–20 keV under these new conditions.
•An increase of the upper limit of the energy of epithermal neutrons for BNCT has been proposed.•A fast computer code for evaluating dose depth profiles for BNCT has been introduced.•Useful analytical parametrizations of the different dose components for a standard tissue have been obtained.•Figures of merit for different neutron energies have been calculated and their dependence on the energy has been discussed.</abstract><cop>Oxford</cop><pub>Elsevier Ltd</pub><doi>10.1016/j.radphyschem.2018.11.015</doi><tpages>5</tpages></addata></record> |
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| ispartof | Radiation physics and chemistry (Oxford, England : 1993), 2019-03, Vol.156, p.240-244 |
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| language | eng |
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| source | Elsevier ScienceDirect Journals Complete - AutoHoldings |
| subjects | Accelerators BNCT Boron Dose depth profile Fast neutrons Monte Carlo simulations Neutron spectra Neutrons Nuclear capture Therapy |
| title | On the upper limit for the energy of epithermal neutrons for Boron Neutron Capture Therapy |
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