Ischemic preconditioning reveals that GLT1 EAAT2 glutamate transporter is a novel PPAR target gene involved in neuroprotection
Excessive levels of extracellular glutamate in the nervous system are excitotoxic and lead to neuronal death. Glutamate transport, mainly by glutamate transporter GLT1/EAAT2, is the only mechanism for maintaining extracellular glutamate concentrations below excitotoxic levels in the central nervous...
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Veröffentlicht in: | Journal of cerebral blood flow and metabolism 2007-07, Vol.27 (7), p.1327-1338 |
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Hauptverfasser: | , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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