Ischemic preconditioning reveals that GLT1 EAAT2 glutamate transporter is a novel PPAR target gene involved in neuroprotection

Excessive levels of extracellular glutamate in the nervous system are excitotoxic and lead to neuronal death. Glutamate transport, mainly by glutamate transporter GLT1/EAAT2, is the only mechanism for maintaining extracellular glutamate concentrations below excitotoxic levels in the central nervous...

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Veröffentlicht in:Journal of cerebral blood flow and metabolism 2007-07, Vol.27 (7), p.1327-1338
Hauptverfasser: Romera, Cristina, Hurtado, Olivia, Mallolas, Judith, Pereira, Marta P, Morales, Jesús R, Romera, Alejandro, Serena, Joaquín, Vivancos, José, Nombela, Florentino, Lorenzo, Pedro, Lizasoain, Ignacio, Moro, Maria A
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Sprache:eng
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