Formulation and evaluation of immediate release tablet of risperidone

Risperidone immediate tablets were prepared by directs compression technique as per the formula given in the Table 1 The superdisintegrants such as kollidon and citric acid were used in different proportions2'3 Procedure: All the ingredients were passed through sieve #40 and were subjected for...

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Veröffentlicht in:Research journal of pharmacy and technology 2018-06, Vol.11 (6), p.2301-2305
Hauptverfasser: Deepika, Alexander, Amit, Agrawal, Palak, Banjare, Tripti, Bhatt, Aditi, Gupta, Swapnil, Bhandarkar, Akansha, Sahu, Hemlata, Diwedi, Shradha Devi, Sahu, Siddharth Kumar, Yadav, Pooja, Sahu, Kailash, Dewangan, Deeksha, Thapa, Hemlata, Sahu, Pankaj, Soni, Sonam, Singh, Ajay, Sharma, Mukesh, Tripathi, D. K., Ajazuddin
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container_end_page 2305
container_issue 6
container_start_page 2301
container_title Research journal of pharmacy and technology
container_volume 11
creator Deepika
Alexander, Amit
Agrawal, Palak
Banjare, Tripti
Bhatt, Aditi
Gupta, Swapnil
Bhandarkar, Akansha
Sahu, Hemlata
Diwedi, Shradha Devi
Sahu, Siddharth Kumar
Yadav, Pooja
Sahu, Kailash
Dewangan, Deeksha
Thapa, Hemlata
Sahu, Pankaj
Soni, Sonam
Singh, Ajay
Sharma, Mukesh
Tripathi, D. K.
Ajazuddin
description Risperidone immediate tablets were prepared by directs compression technique as per the formula given in the Table 1 The superdisintegrants such as kollidon and citric acid were used in different proportions2'3 Procedure: All the ingredients were passed through sieve #40 and were subjected for drying to remove moisture content . Experimental Data: Preparation of hydrochloric acid (0.1N) solution: A volume of 8.5 ml of concentration HCL was accurately measured using 10ml pipette and transferred into clean 100ml volumetric flask diluted with water solution prepared and shaken thoroughly Preparation of risperdione standard stock solution with (0.1N )Hcl solution: The absorbance of each solution was measured at 236nm using UV spectrophotometer photometric mode.6-8 Calibration curve of Risperidone in 0.1 N hydrochloric acid solution: [...]it should follow first order kinetics profile, if it claims to release the drug initially very quickly.
doi_str_mv 10.5958/0974-360X.2018.00426.2
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subjects Antipsychotics
Bipolar disorder
Drug delivery systems
Drug dosages
Hydrochloric acid
Hydrogels
Nonsteroidal anti-inflammatory drugs
Pharmaceuticals
Pharmacy
Psychosis
Psychotropic drugs
Schizophrenia
title Formulation and evaluation of immediate release tablet of risperidone
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