Formulation and evaluation of immediate release tablet of risperidone
Risperidone immediate tablets were prepared by directs compression technique as per the formula given in the Table 1 The superdisintegrants such as kollidon and citric acid were used in different proportions2'3 Procedure: All the ingredients were passed through sieve #40 and were subjected for...
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Veröffentlicht in: | Research journal of pharmacy and technology 2018-06, Vol.11 (6), p.2301-2305 |
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creator | Deepika Alexander, Amit Agrawal, Palak Banjare, Tripti Bhatt, Aditi Gupta, Swapnil Bhandarkar, Akansha Sahu, Hemlata Diwedi, Shradha Devi Sahu, Siddharth Kumar Yadav, Pooja Sahu, Kailash Dewangan, Deeksha Thapa, Hemlata Sahu, Pankaj Soni, Sonam Singh, Ajay Sharma, Mukesh Tripathi, D. K. Ajazuddin |
description | Risperidone immediate tablets were prepared by directs compression technique as per the formula given in the Table 1 The superdisintegrants such as kollidon and citric acid were used in different proportions2'3 Procedure: All the ingredients were passed through sieve #40 and were subjected for drying to remove moisture content . Experimental Data: Preparation of hydrochloric acid (0.1N) solution: A volume of 8.5 ml of concentration HCL was accurately measured using 10ml pipette and transferred into clean 100ml volumetric flask diluted with water solution prepared and shaken thoroughly Preparation of risperdione standard stock solution with (0.1N )Hcl solution: The absorbance of each solution was measured at 236nm using UV spectrophotometer photometric mode.6-8 Calibration curve of Risperidone in 0.1 N hydrochloric acid solution: [...]it should follow first order kinetics profile, if it claims to release the drug initially very quickly. |
doi_str_mv | 10.5958/0974-360X.2018.00426.2 |
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Experimental Data: Preparation of hydrochloric acid (0.1N) solution: A volume of 8.5 ml of concentration HCL was accurately measured using 10ml pipette and transferred into clean 100ml volumetric flask diluted with water solution prepared and shaken thoroughly Preparation of risperdione standard stock solution with (0.1N )Hcl solution: The absorbance of each solution was measured at 236nm using UV spectrophotometer photometric mode.6-8 Calibration curve of Risperidone in 0.1 N hydrochloric acid solution: [...]it should follow first order kinetics profile, if it claims to release the drug initially very quickly.</description><identifier>ISSN: 0974-3618</identifier><identifier>EISSN: 0974-360X</identifier><identifier>EISSN: 0974-306X</identifier><identifier>DOI: 10.5958/0974-360X.2018.00426.2</identifier><language>eng</language><publisher>Raipur: A&V Publications</publisher><subject>Antipsychotics ; Bipolar disorder ; Drug delivery systems ; Drug dosages ; Hydrochloric acid ; Hydrogels ; Nonsteroidal anti-inflammatory drugs ; Pharmaceuticals ; Pharmacy ; Psychosis ; Psychotropic drugs ; Schizophrenia</subject><ispartof>Research journal of pharmacy and technology, 2018-06, Vol.11 (6), p.2301-2305</ispartof><rights>Copyright A&V Publications Jun 2018</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c198t-3507dc8227351ce66b915f2180bfc6f4e34e66b7183a52ee2f631667a191c2133</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Deepika</creatorcontrib><creatorcontrib>Alexander, Amit</creatorcontrib><creatorcontrib>Agrawal, Palak</creatorcontrib><creatorcontrib>Banjare, Tripti</creatorcontrib><creatorcontrib>Bhatt, Aditi</creatorcontrib><creatorcontrib>Gupta, Swapnil</creatorcontrib><creatorcontrib>Bhandarkar, Akansha</creatorcontrib><creatorcontrib>Sahu, Hemlata</creatorcontrib><creatorcontrib>Diwedi, Shradha Devi</creatorcontrib><creatorcontrib>Sahu, Siddharth Kumar</creatorcontrib><creatorcontrib>Yadav, Pooja</creatorcontrib><creatorcontrib>Sahu, Kailash</creatorcontrib><creatorcontrib>Dewangan, Deeksha</creatorcontrib><creatorcontrib>Thapa, Hemlata</creatorcontrib><creatorcontrib>Sahu, Pankaj</creatorcontrib><creatorcontrib>Soni, Sonam</creatorcontrib><creatorcontrib>Singh, Ajay</creatorcontrib><creatorcontrib>Sharma, Mukesh</creatorcontrib><creatorcontrib>Tripathi, D. K.</creatorcontrib><creatorcontrib>Ajazuddin</creatorcontrib><title>Formulation and evaluation of immediate release tablet of risperidone</title><title>Research journal of pharmacy and technology</title><description>Risperidone immediate tablets were prepared by directs compression technique as per the formula given in the Table 1 The superdisintegrants such as kollidon and citric acid were used in different proportions2'3 Procedure: All the ingredients were passed through sieve #40 and were subjected for drying to remove moisture content . Experimental Data: Preparation of hydrochloric acid (0.1N) solution: A volume of 8.5 ml of concentration HCL was accurately measured using 10ml pipette and transferred into clean 100ml volumetric flask diluted with water solution prepared and shaken thoroughly Preparation of risperdione standard stock solution with (0.1N )Hcl solution: The absorbance of each solution was measured at 236nm using UV spectrophotometer photometric mode.6-8 Calibration curve of Risperidone in 0.1 N hydrochloric acid solution: [...]it should follow first order kinetics profile, if it claims to release the drug initially very quickly.</description><subject>Antipsychotics</subject><subject>Bipolar disorder</subject><subject>Drug delivery systems</subject><subject>Drug dosages</subject><subject>Hydrochloric acid</subject><subject>Hydrogels</subject><subject>Nonsteroidal anti-inflammatory drugs</subject><subject>Pharmaceuticals</subject><subject>Pharmacy</subject><subject>Psychosis</subject><subject>Psychotropic drugs</subject><subject>Schizophrenia</subject><issn>0974-3618</issn><issn>0974-360X</issn><issn>0974-306X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNo9kE9LxDAQxYMouKz7FaTguTWTNGlylGVXhQUvCt5C2k6gS9vUpBX89rZWdi7z5z3ewI-Qe6CZ0EI9Ul3kKZf0M2MUVEZpzmTGrsjmIlxfZlC3ZBfjmc4llWC52pDD0Yduau3Y-D6xfZ3gt22ndfUuaboO68aOmARs0UZMRlu2OC5aaOKAoal9j3fkxtk24u6_b8nH8fC-f0lPb8-v-6dTWoFWY8oFLepKMVZwARVKWWoQjoGipauky5Hny7EAxa1giMxJDlIWFjRUDDjfkoc1dwj-a8I4mrOfQj-_NAy0oCpXXMwuubqq4GMM6MwQms6GHwPULNTMAsQscMxCzfxRM4z_AlqMXvE</recordid><startdate>20180601</startdate><enddate>20180601</enddate><creator>Deepika</creator><creator>Alexander, Amit</creator><creator>Agrawal, Palak</creator><creator>Banjare, Tripti</creator><creator>Bhatt, Aditi</creator><creator>Gupta, Swapnil</creator><creator>Bhandarkar, Akansha</creator><creator>Sahu, Hemlata</creator><creator>Diwedi, Shradha Devi</creator><creator>Sahu, Siddharth Kumar</creator><creator>Yadav, Pooja</creator><creator>Sahu, Kailash</creator><creator>Dewangan, Deeksha</creator><creator>Thapa, Hemlata</creator><creator>Sahu, Pankaj</creator><creator>Soni, Sonam</creator><creator>Singh, Ajay</creator><creator>Sharma, Mukesh</creator><creator>Tripathi, D. 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Experimental Data: Preparation of hydrochloric acid (0.1N) solution: A volume of 8.5 ml of concentration HCL was accurately measured using 10ml pipette and transferred into clean 100ml volumetric flask diluted with water solution prepared and shaken thoroughly Preparation of risperdione standard stock solution with (0.1N )Hcl solution: The absorbance of each solution was measured at 236nm using UV spectrophotometer photometric mode.6-8 Calibration curve of Risperidone in 0.1 N hydrochloric acid solution: [...]it should follow first order kinetics profile, if it claims to release the drug initially very quickly.</abstract><cop>Raipur</cop><pub>A&V Publications</pub><doi>10.5958/0974-360X.2018.00426.2</doi><tpages>5</tpages></addata></record> |
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subjects | Antipsychotics Bipolar disorder Drug delivery systems Drug dosages Hydrochloric acid Hydrogels Nonsteroidal anti-inflammatory drugs Pharmaceuticals Pharmacy Psychosis Psychotropic drugs Schizophrenia |
title | Formulation and evaluation of immediate release tablet of risperidone |
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