Mitochondria in activated microglia in vitro

In the CNS, microglia become activated, i.e. change their functional state and phenotype, in response to a wide variety of pathological stimuli. Since this activation is triggered at a very low threshold and at the same time remains territorially restricted, the spatial distribution of activated mic...

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Veröffentlicht in:	Brain cell biology 2004-09, Vol.33 (5), p.535-541
Hauptverfasser:	Banati, Richard B, Egensperger, Rupert, Maassen, Alexander, Hager, Gerhard, Kreutzberg, Georg W, Graeber, Manuel B
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents - metabolism Benzimidazoles Binding Sites - drug effects Binding Sites - physiology Carbocyanines Carrier Proteins - drug effects Carrier Proteins - metabolism Cell Shape - drug effects Cell Shape - physiology Cells, Cultured Fluorescent Dyes Gliosis - chemically induced Gliosis - metabolism Gliosis - physiopathology Inflammation Mediators - pharmacology Intracellular Membranes - metabolism Intracellular Membranes - ultrastructure Isoquinolines - metabolism Isoquinolines - pharmacokinetics Membrane Potentials - drug effects Membrane Potentials - physiology Microglia - drug effects Microglia - metabolism Microglia - ultrastructure Microscopy, Confocal Microscopy, Electron, Transmission Mitochondria - drug effects Mitochondria - metabolism Mitochondria - ultrastructure Rats Receptors, GABA-A - drug effects Receptors, GABA-A - metabolism Up-Regulation - drug effects Up-Regulation - physiology
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