Effect of glucose and palmitate environment on proliferation and migration of PC3‐prostate cancer cells

Recent studies have been trying to find out how diet and metabolic changes such as dyslipidaemia, hyperglycaemia, and hyperinsulinaemia can stimulate cancer progression. This investigation aimed to evaluate the effect of high concentrations of fatty acids and/or glucose in tumour prostate cells, foc...

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Veröffentlicht in:	Cell biology international 2019-04, Vol.43 (4), p.373-383
Hauptverfasser:	Rezende, Lívia Prometti, Galheigo, Maria Raquel Unterkircher, Landim, Breno Costa, Cruz, Amanda Rodrigues, Botelho, Françoise Vasconcelos, Zanon, Renata Graciele, Góes, Rejane Maira, Ribeiro, Daniele Lisboa
Format:	Artikel
Sprache:	eng
Schlagworte:	AMPK Antioxidants Carcinogenesis Catalase Cell adhesion & migration Cell growth Cell migration Cell Movement - drug effects Cell proliferation Cell Proliferation - drug effects Dyslipidemia Fatty acids Fatty Acids - metabolism Glucose Glucose - adverse effects Glucose - metabolism Glucose - physiology Humans Hyperglycemia Hyperinsulinism - metabolism Insulin - metabolism Male Oxidative stress palmitate Palmitates - metabolism Palmitates - pharmacology Palmitic acid PC-3 Cells - drug effects Phosphorylation Prostate - metabolism Prostate cancer Prostatic Neoplasms - metabolism saturated fatty acid Tumors
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