Cytotoxicity of Natural Alantolactones Conjugated to Substituted Piperazines

Previously unknown conjugates of substituted piperazines with various functional groups on the N atom and the natural sesquiterpene lactones alantolactone, isoalantolactone, and alloalantolactone, the main constituents of the plant Inula helenium , were synthesized using Michael reaction. Cytotoxici...

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Veröffentlicht in:	Chemistry of natural compounds 2019-01, Vol.55 (1), p.41-46
Hauptverfasser:	Pukhov, S. A., Afanas’eva, S. V., Anikina, L. V., Kozlovskii, V. I., Neganova, M. E., Klochkov, S. G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Caprolactone Chemical synthesis Conjugates Cytotoxicity Functional groups Lactones Medicine Michael reaction Organic Chemistry Pharmacy Plant Sciences Substitutes Toxicity Tumors
Online-Zugang:	Volltext
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