Oxcarbazepine in Rapid Benzodiazepine Detoxification
Objective: This study aims at evaluating the tolerability and efficacy of the antiepileptic drug oxcarbazepine in benzodiazepine detoxification in ten patients. Methods: In this case study of an inpatient withdrawal program, each of the ten patients was detoxified using oxcarbazepine and completed w...
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| Veröffentlicht in: | The American journal of drug and alcohol abuse 2008-01, Vol.34 (5), p.534-540 |
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| container_title | The American journal of drug and alcohol abuse |
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| creator | Croissant, Bernhard Grosshans, Martin Diehl, Alexander Mann, Karl |
| description | Objective: This study aims at evaluating the tolerability and efficacy of the antiepileptic drug oxcarbazepine in benzodiazepine detoxification in ten patients. Methods: In this case study of an inpatient withdrawal program, each of the ten patients was detoxified using oxcarbazepine and completed withdrawal successfully without the occurrence of withdrawal symptoms. The detoxification program followed an outlined dosage scheme with oxcarbazepine increase and benzodiazepine tapering. Results: The rapidity of benzodiazepine detoxification using oxcarbazepine was remarkable, benzodiazepine withdrawal being completed in as little as 11 days. Conclusions: The results support the assumption that oxcarbazepine is a valuable drug for inpatient benzodiazepine withdrawal programs. |
| doi_str_mv | 10.1080/00952990802149021 |
| format | Article |
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Methods: In this case study of an inpatient withdrawal program, each of the ten patients was detoxified using oxcarbazepine and completed withdrawal successfully without the occurrence of withdrawal symptoms. The detoxification program followed an outlined dosage scheme with oxcarbazepine increase and benzodiazepine tapering. Results: The rapidity of benzodiazepine detoxification using oxcarbazepine was remarkable, benzodiazepine withdrawal being completed in as little as 11 days. Conclusions: The results support the assumption that oxcarbazepine is a valuable drug for inpatient benzodiazepine withdrawal programs.</description><identifier>ISSN: 0095-2990</identifier><identifier>EISSN: 1097-9891</identifier><identifier>DOI: 10.1080/00952990802149021</identifier><identifier>PMID: 18821451</identifier><identifier>CODEN: AJDABD</identifier><language>eng</language><publisher>Colchester: Informa UK Ltd</publisher><subject>Addictive behaviors ; Adult ; Adult and adolescent clinical studies ; Aged, 80 and over ; Anticonvulsants - administration & dosage ; Anticonvulsants - adverse effects ; Anticonvulsants - therapeutic use ; Benzodiazepine detoxification ; Benzodiazepines - adverse effects ; Biological and medical sciences ; carbamazepine ; Carbamazepine - administration & dosage ; Carbamazepine - adverse effects ; Carbamazepine - analogs & derivatives ; Carbamazepine - therapeutic use ; Detoxification ; dosage scheme ; Drug abuse ; Drug Addiction ; Drug dosages ; Female ; Follow-Up Studies ; Humans ; Male ; Medical sciences ; Medications ; Middle Aged ; Neuropharmacology ; oxcarbazepine ; Pharmacology ; Pharmacology. Drug treatments ; Prescription drugs ; Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer ; Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; Psychopharmacology ; Substance abuse treatment ; Substance Abuse Treatment Centers ; Substance Withdrawal Syndrome - drug therapy ; Time Factors ; Treatment Methods ; Treatment Outcome ; withdrawal symptoms</subject><ispartof>The American journal of drug and alcohol abuse, 2008-01, Vol.34 (5), p.534-540</ispartof><rights>2008 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 2008</rights><rights>2008 INIST-CNRS</rights><rights>Copyright Marcel Dekker, Inc. 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Methods: In this case study of an inpatient withdrawal program, each of the ten patients was detoxified using oxcarbazepine and completed withdrawal successfully without the occurrence of withdrawal symptoms. The detoxification program followed an outlined dosage scheme with oxcarbazepine increase and benzodiazepine tapering. Results: The rapidity of benzodiazepine detoxification using oxcarbazepine was remarkable, benzodiazepine withdrawal being completed in as little as 11 days. Conclusions: The results support the assumption that oxcarbazepine is a valuable drug for inpatient benzodiazepine withdrawal programs.</description><subject>Addictive behaviors</subject><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>Aged, 80 and over</subject><subject>Anticonvulsants - administration & dosage</subject><subject>Anticonvulsants - adverse effects</subject><subject>Anticonvulsants - therapeutic use</subject><subject>Benzodiazepine detoxification</subject><subject>Benzodiazepines - adverse effects</subject><subject>Biological and medical sciences</subject><subject>carbamazepine</subject><subject>Carbamazepine - administration & dosage</subject><subject>Carbamazepine - adverse effects</subject><subject>Carbamazepine - analogs & derivatives</subject><subject>Carbamazepine - therapeutic use</subject><subject>Detoxification</subject><subject>dosage scheme</subject><subject>Drug abuse</subject><subject>Drug Addiction</subject><subject>Drug dosages</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Medications</subject><subject>Middle Aged</subject><subject>Neuropharmacology</subject><subject>oxcarbazepine</subject><subject>Pharmacology</subject><subject>Pharmacology. Drug treatments</subject><subject>Prescription drugs</subject><subject>Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer</subject><subject>Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Psychopharmacology</subject><subject>Substance abuse treatment</subject><subject>Substance Abuse Treatment Centers</subject><subject>Substance Withdrawal Syndrome - drug therapy</subject><subject>Time Factors</subject><subject>Treatment Methods</subject><subject>Treatment Outcome</subject><subject>withdrawal symptoms</subject><issn>0095-2990</issn><issn>1097-9891</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><sourceid>BHHNA</sourceid><recordid>eNp9kVtLxDAQhYMoul5-gC-yCPpWnaRpm6Avul5hQRB9LtM0xUjbrEmLur_eLLurqOhLEma-M8w5IWSXwhEFAccAMmFShiejXIZjhQwoyCySQtJVMpj1oxmwQTa9fwYAKjK-TjaoEEGR0AHhd28KXYFTPTGtHpp2eI8TUw7PdTu1pVnWL3Rn30xlFHbGtttkrcLa653FvUUery4fRjfR-O76dnQ2jhSXrIsoxsh1GQuFVaqyVGIKmSwEQiqQU5XFrEpDX5ZAkzQGIWMolCpYAoXUmYi3yOF87sTZl177Lm-MV7qusdW293lKOeM8TQK4_wN8tr1rw245ozLmnGUQIDqHlLPeO13lE2cadO85hXyWZ_4rz6DZWwzui0aXX4pFgAE4WADoFdaVw1YZ_8kxyII1MbNyOudMW1nX4Kt1dZl3-F5btxTF_-1x8k3-pLHunsLP6S-nf6s_AP7soFI</recordid><startdate>20080101</startdate><enddate>20080101</enddate><creator>Croissant, Bernhard</creator><creator>Grosshans, Martin</creator><creator>Diehl, Alexander</creator><creator>Mann, Karl</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><general>Taylor & Francis Ltd</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QJ</scope><scope>7U3</scope><scope>BHHNA</scope><scope>K7.</scope><scope>K9.</scope></search><sort><creationdate>20080101</creationdate><title>Oxcarbazepine in Rapid Benzodiazepine Detoxification</title><author>Croissant, Bernhard ; Grosshans, Martin ; Diehl, Alexander ; Mann, Karl</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c492t-1a3a4ed38caf6c769a6079b8a068a41c732f6ed39d0156308930bccb250b9e783</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Addictive behaviors</topic><topic>Adult</topic><topic>Adult and adolescent clinical studies</topic><topic>Aged, 80 and over</topic><topic>Anticonvulsants - administration & dosage</topic><topic>Anticonvulsants - adverse effects</topic><topic>Anticonvulsants - therapeutic use</topic><topic>Benzodiazepine detoxification</topic><topic>Benzodiazepines - adverse effects</topic><topic>Biological and medical sciences</topic><topic>carbamazepine</topic><topic>Carbamazepine - administration & dosage</topic><topic>Carbamazepine - adverse effects</topic><topic>Carbamazepine - analogs & derivatives</topic><topic>Carbamazepine - therapeutic use</topic><topic>Detoxification</topic><topic>dosage scheme</topic><topic>Drug abuse</topic><topic>Drug Addiction</topic><topic>Drug dosages</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Medications</topic><topic>Middle Aged</topic><topic>Neuropharmacology</topic><topic>oxcarbazepine</topic><topic>Pharmacology</topic><topic>Pharmacology. 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Psychiatry</topic><topic>Psychopharmacology</topic><topic>Substance abuse treatment</topic><topic>Substance Abuse Treatment Centers</topic><topic>Substance Withdrawal Syndrome - drug therapy</topic><topic>Time Factors</topic><topic>Treatment Methods</topic><topic>Treatment Outcome</topic><topic>withdrawal symptoms</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Croissant, Bernhard</creatorcontrib><creatorcontrib>Grosshans, Martin</creatorcontrib><creatorcontrib>Diehl, Alexander</creatorcontrib><creatorcontrib>Mann, Karl</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>Social Services Abstracts</collection><collection>Sociological Abstracts</collection><collection>ProQuest Criminal Justice (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><jtitle>The American journal of drug and alcohol abuse</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Croissant, Bernhard</au><au>Grosshans, Martin</au><au>Diehl, Alexander</au><au>Mann, Karl</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Oxcarbazepine in Rapid Benzodiazepine Detoxification</atitle><jtitle>The American journal of drug and alcohol abuse</jtitle><addtitle>Am J Drug Alcohol Abuse</addtitle><date>2008-01-01</date><risdate>2008</risdate><volume>34</volume><issue>5</issue><spage>534</spage><epage>540</epage><pages>534-540</pages><issn>0095-2990</issn><eissn>1097-9891</eissn><coden>AJDABD</coden><abstract>Objective: This study aims at evaluating the tolerability and efficacy of the antiepileptic drug oxcarbazepine in benzodiazepine detoxification in ten patients. 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| subjects | Addictive behaviors Adult Adult and adolescent clinical studies Aged, 80 and over Anticonvulsants - administration & dosage Anticonvulsants - adverse effects Anticonvulsants - therapeutic use Benzodiazepine detoxification Benzodiazepines - adverse effects Biological and medical sciences carbamazepine Carbamazepine - administration & dosage Carbamazepine - adverse effects Carbamazepine - analogs & derivatives Carbamazepine - therapeutic use Detoxification dosage scheme Drug abuse Drug Addiction Drug dosages Female Follow-Up Studies Humans Male Medical sciences Medications Middle Aged Neuropharmacology oxcarbazepine Pharmacology Pharmacology. Drug treatments Prescription drugs Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychopharmacology Substance abuse treatment Substance Abuse Treatment Centers Substance Withdrawal Syndrome - drug therapy Time Factors Treatment Methods Treatment Outcome withdrawal symptoms |
| title | Oxcarbazepine in Rapid Benzodiazepine Detoxification |
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