Genetic Segregation Analysis of Alcohol and Other Substance-Use Disorders in Families with Recurrent, Early-Onset Major Depression

Objective: The goal of this study was to conduct a complex segregation analysis of alcohol and other substance-use disorders in families identified by probands with recurrent, early-onset major depression (RE-MDD). Method: Eighty-one families were identified through probands over the age of 18, who...

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Veröffentlicht in:	The American journal of drug and alcohol abuse 2002-01, Vol.28 (4), p.711-731
Hauptverfasser:	Maher, Brion S., Marazita, Mary L., Zubenko, Wendy N., Kaplan, Barry B., Zubenko, George S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adult and adolescent clinical studies Age Factors Aged Alcohol use disorders Alcohol-Related Disorders - genetics Alcoholism Biological and medical sciences Chromosome Segregation - genetics Complex segregation analysis Depression Depressive Disorder - epidemiology Depressive Disorder - genetics Families & family life Family Female Genetics Humans Major depression Male Medical sciences Mental depression Middle Aged Mood disorders Phenotype Prevalence Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Reproducibility of Results Sex Factors Substance-Related Disorders - genetics Substance-use disorders
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