Genistein action in the prepubertal mammary gland in a chemoprevention model

A diet high in soy is associated with many health benefits, including reduced incidence of breast cancer. The soy phytoestrogen, genistein, is hypothesized to contribute to mammary chemoprevention via interaction with estrogen receptors (ERs) alpha and/or beta. These steroid signaling pathways are b...

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Veröffentlicht in:	Carcinogenesis (New York) 2002-09, Vol.23 (9), p.1467-1474
Hauptverfasser:	Cotroneo, Michelle S., Wang, Jun, Fritz, Wayne A., Eltoum, Isam-Eldin, Lamartiniere, Coral A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anticarcinogenic Agents - pharmacology Apoptosis Biological and medical sciences Blotting, Western Breast - cytology Breast - drug effects Breast - growth & development Carcinogenesis, carcinogens and anticarcinogens Cell Differentiation - drug effects Chemoprevention dimethylsulfoxide DMSO EGF epidermal growth factor ErbB Receptors - metabolism ERK ERs Estradiol - administration & dosage Estradiol - analogs & derivatives Estradiol - pharmacology estradiol benzoate Estrogen Receptor alpha estrogen receptors extracellular signal regulated kinases Female Foods and miscellaneous Fulvestrant Genistein - pharmacology Keratins - biosynthesis Medical sciences MEK mitogen activating kinase kinase Models, Animal Phosphotransferases - analysis progesterone receptor Rats Rats, Sprague-Dawley Receptors, Estrogen - metabolism Receptors, Progesterone - biosynthesis TEB terminal end buds Tumors
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