Dimensions and wall force development capacity of human pial arteries from normotensives is not altered in obesity
The dimensions and maximum wall tension capacity of segments of human pial arteries from normotensive obese and non-obese patients were compared. Segment size was assessed by quantitative morphometry of fixed sections and wall force by in vitro myography. Twenty normotensive non-obese and 13 normote...
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| Veröffentlicht in: | International Journal of Obesity 2001-05, Vol.25 (5), p.756-758 |
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| container_title | International Journal of Obesity |
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| creator | BEVAN, J. A DODGE, J WALTERS, Ci WELLMAN, T BEVAN, R. D |
| description | The dimensions and maximum wall tension capacity of segments of human pial arteries from normotensive obese and non-obese patients were compared.
Segment size was assessed by quantitative morphometry of fixed sections and wall force by in vitro myography.
Twenty normotensive non-obese and 13 normotensive obese humans body mass index (BMI) 22.4+/-0.5 and 33.9+/-1.7 kg/m(2), respectively) were studied.
There was no significant difference in the perimeter of the outer medial border, the smoothed out length of the internal elastic lamina, the ratios of media thickness to area and lumen diameter and the maximum wall force development between the two groups.
Obesity per se is not associated with initial dimensional changes nor capacity to develop wall tension that might lead to the emergence of hypertension. |
| doi_str_mv | 10.1038/sj.ijo.0801600 |
| format | Article |
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Segment size was assessed by quantitative morphometry of fixed sections and wall force by in vitro myography.
Twenty normotensive non-obese and 13 normotensive obese humans body mass index (BMI) 22.4+/-0.5 and 33.9+/-1.7 kg/m(2), respectively) were studied.
There was no significant difference in the perimeter of the outer medial border, the smoothed out length of the internal elastic lamina, the ratios of media thickness to area and lumen diameter and the maximum wall force development between the two groups.
Obesity per se is not associated with initial dimensional changes nor capacity to develop wall tension that might lead to the emergence of hypertension.</description><identifier>ISSN: 0307-0565</identifier><identifier>EISSN: 1476-5497</identifier><identifier>DOI: 10.1038/sj.ijo.0801600</identifier><identifier>PMID: 11360162</identifier><identifier>CODEN: IJOBDP</identifier><language>eng</language><publisher>Basingstoke: Nature Publishing</publisher><subject>Adolescent ; Adult ; Aged ; Arterial hypertension. Arterial hypotension ; Biological and medical sciences ; Blood and lymphatic vessels ; Blood pressure ; Body mass index ; Cardiology. Vascular system ; Cerebral Arteries - anatomy & histology ; Cerebral Arteries - physiology ; Cerebrovascular Circulation ; Clinical manifestations. Epidemiology. Investigative techniques. Etiology ; Humans ; Hypertension ; Hypertension - etiology ; Insulin ; Medical sciences ; Metabolic diseases ; Metabolism ; Middle Aged ; Obesity ; Obesity - complications ; Obesity - physiopathology ; Trends ; Veins & arteries ; Weight control</subject><ispartof>International Journal of Obesity, 2001-05, Vol.25 (5), p.756-758</ispartof><rights>2001 INIST-CNRS</rights><rights>Copyright Nature Publishing Group May 2001</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c315t-7d7fbfa908fcf3ec9fd04c056e69b7b491b19982ac97d477a4dbfb019e01a77f3</citedby><cites>FETCH-LOGICAL-c315t-7d7fbfa908fcf3ec9fd04c056e69b7b491b19982ac97d477a4dbfb019e01a77f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=965429$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11360162$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>BEVAN, J. A</creatorcontrib><creatorcontrib>DODGE, J</creatorcontrib><creatorcontrib>WALTERS, Ci</creatorcontrib><creatorcontrib>WELLMAN, T</creatorcontrib><creatorcontrib>BEVAN, R. D</creatorcontrib><title>Dimensions and wall force development capacity of human pial arteries from normotensives is not altered in obesity</title><title>International Journal of Obesity</title><addtitle>Int J Obes Relat Metab Disord</addtitle><description>The dimensions and maximum wall tension capacity of segments of human pial arteries from normotensive obese and non-obese patients were compared.
Segment size was assessed by quantitative morphometry of fixed sections and wall force by in vitro myography.
Twenty normotensive non-obese and 13 normotensive obese humans body mass index (BMI) 22.4+/-0.5 and 33.9+/-1.7 kg/m(2), respectively) were studied.
There was no significant difference in the perimeter of the outer medial border, the smoothed out length of the internal elastic lamina, the ratios of media thickness to area and lumen diameter and the maximum wall force development between the two groups.
Obesity per se is not associated with initial dimensional changes nor capacity to develop wall tension that might lead to the emergence of hypertension.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Arterial hypertension. Arterial hypotension</subject><subject>Biological and medical sciences</subject><subject>Blood and lymphatic vessels</subject><subject>Blood pressure</subject><subject>Body mass index</subject><subject>Cardiology. Vascular system</subject><subject>Cerebral Arteries - anatomy & histology</subject><subject>Cerebral Arteries - physiology</subject><subject>Cerebrovascular Circulation</subject><subject>Clinical manifestations. Epidemiology. Investigative techniques. Etiology</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Hypertension - etiology</subject><subject>Insulin</subject><subject>Medical sciences</subject><subject>Metabolic diseases</subject><subject>Metabolism</subject><subject>Middle Aged</subject><subject>Obesity</subject><subject>Obesity - complications</subject><subject>Obesity - physiopathology</subject><subject>Trends</subject><subject>Veins & arteries</subject><subject>Weight control</subject><issn>0307-0565</issn><issn>1476-5497</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNpFkE1LxDAQhoMo7rp69ShBz62TfqU5yvoJC170XKZpgiltU5Puyv57s2zR08DMM-8wDyHXDGIGaXnv29i0NoYSWAFwQpYs40WUZ4KfkiWkwCPIi3xBLrxvASDPITknC8bSIiwkS-IeTa8Gb-zgKQ4N_cGuo9o6qWijdqqzYxhPVOKI0kx7ajX92vY40NFgR9FNyhnlqXa2p4N1vZ0OabvQMj40JopdQFRDzUBtrXzIuCRnGjuvrua6Ip_PTx_r12jz_vK2fthEMmX5FPGG61qjgFJLnSopdAOZDN-oQtS8zgSrmRBlglLwJuMcs6bWNTChgCHnOl2R22Pu6Oz3Vvmpau3WDeFklTAR1ECeBSg-QtJZ753S1ehMj25fMagOhivfVsFwNRsOCzdz6rbuVfOPz0oDcDcD6CV22uEgjf_jRJFniUh_AaQVhp0</recordid><startdate>20010501</startdate><enddate>20010501</enddate><creator>BEVAN, J. 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A</au><au>DODGE, J</au><au>WALTERS, Ci</au><au>WELLMAN, T</au><au>BEVAN, R. D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dimensions and wall force development capacity of human pial arteries from normotensives is not altered in obesity</atitle><jtitle>International Journal of Obesity</jtitle><addtitle>Int J Obes Relat Metab Disord</addtitle><date>2001-05-01</date><risdate>2001</risdate><volume>25</volume><issue>5</issue><spage>756</spage><epage>758</epage><pages>756-758</pages><issn>0307-0565</issn><eissn>1476-5497</eissn><coden>IJOBDP</coden><abstract>The dimensions and maximum wall tension capacity of segments of human pial arteries from normotensive obese and non-obese patients were compared.
Segment size was assessed by quantitative morphometry of fixed sections and wall force by in vitro myography.
Twenty normotensive non-obese and 13 normotensive obese humans body mass index (BMI) 22.4+/-0.5 and 33.9+/-1.7 kg/m(2), respectively) were studied.
There was no significant difference in the perimeter of the outer medial border, the smoothed out length of the internal elastic lamina, the ratios of media thickness to area and lumen diameter and the maximum wall force development between the two groups.
Obesity per se is not associated with initial dimensional changes nor capacity to develop wall tension that might lead to the emergence of hypertension.</abstract><cop>Basingstoke</cop><pub>Nature Publishing</pub><pmid>11360162</pmid><doi>10.1038/sj.ijo.0801600</doi><tpages>3</tpages></addata></record> |
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| source | MEDLINE; Nature; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; SpringerLink Journals - AutoHoldings |
| subjects | Adolescent Adult Aged Arterial hypertension. Arterial hypotension Biological and medical sciences Blood and lymphatic vessels Blood pressure Body mass index Cardiology. Vascular system Cerebral Arteries - anatomy & histology Cerebral Arteries - physiology Cerebrovascular Circulation Clinical manifestations. Epidemiology. Investigative techniques. Etiology Humans Hypertension Hypertension - etiology Insulin Medical sciences Metabolic diseases Metabolism Middle Aged Obesity Obesity - complications Obesity - physiopathology Trends Veins & arteries Weight control |
| title | Dimensions and wall force development capacity of human pial arteries from normotensives is not altered in obesity |
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