All-trans and 9-cis retinoic acids, retinol and [beta]-carotene chemopreventive activities during the initial phases of hepatocarcinogenesis involve distinct actions on glutathione S-transferase positive preneoplastic lesions remodeling and DNA damage

Chemopreventive activities of all-trans retinoic acid (AtRA), 9-cis retinoic acid (9cRA), retinol (ROL) and β-carotene (βC) were evaluated during hepatocarcinogenesis. Rats received 1 mg/100 g body wt AtRA (AtRA group), 9cRA (9cRA group), ROL (ROL group), 7 mg/100 g body wt βC (βC group) or corn oil...

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Veröffentlicht in:Carcinogenesis (New York) 2005-11, Vol.26 (11), p.1940
Hauptverfasser: Elaine Maria de Almeida Vasconcelos Fonseca, Andrade Chagas, Carlos Eduardo, Mazzantini, Rogério Pietro, Heidor, Renato, Thomas Prates Ong, Fernando Salvador Moreno
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Sprache:eng
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