Dedicated Pinhole SPECT of Intestinal Neutrophil Recruitment in a Mouse Model of Dextran Sulfate Sodium-Induced Colitis

Evaluating the efficacy of therapy in experimental inflammatory bowel disease (IBD) requires information about inflammatory activity in bowel segments or leukocyte recruitment and about kinetics in the follow-up of treatment. This study evaluated a noninvasive scintigraphic technique able to assess...

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Veröffentlicht in:	The Journal of nuclear medicine (1978) 2005-03, Vol.46 (3), p.526
Hauptverfasser:	Bennink, Roelof J, Hamann, Jorg, de Bruin, Kora, ten Kate, Fiebo J.W, van Deventer, Sander J.H, te Velde, Anje A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Colitis - chemically induced Colitis - diagnostic imaging Colitis - metabolism Colitis - pathology Dextran Sulfate Disease Models, Animal Lymphocyte Activation Mice Mice, Inbred BALB C Neutrophils - diagnostic imaging Neutrophils - metabolism Radiopharmaceuticals - pharmacokinetics Technetium Tc 99m Exametazime - pharmacokinetics Tomography, Emission-Computed, Single-Photon - methods
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