Downregulation of telomerase activity in human promyelocytic cell line using RNA interference

Telomerase is a ribonucleoprotein complex. It consists of two main components, human telomerase reverse transcriptase (hTERT) and human telomerase RNA. High telomerase activity is present in most malignant cells, but it is barely detectable in majority of somatic cells. The direct correlation betwee...

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Veröffentlicht in:	Annals of hematology 2009-12, Vol.88 (12), p.1169-1176
Hauptverfasser:	Miri-Moghaddam, E, Deezagi, A, Soheili, Z. S
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Proliferation Down-Regulation Hematology HL-60 Cells - metabolism Humans Medicine Medicine & Public Health Oncology Original Article RNA - genetics RNA - metabolism RNA Interference RNA, Small Interfering - genetics RNA, Small Interfering - metabolism Telomerase - genetics Telomerase - metabolism Transfection
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