Prevalence of pulmonary hypertension and its association with respiratory disturbances in obese patients living at moderately high altitude
OBJECTIVE: To determine the point prevalence of pulmonary hypertension (PH) and its relationship with respiratory disturbances in obese patients living at moderate altitude. SUBJECTS: A total of 57 obese patients comprised the final sample and consisted of 34 women and 23 men, with a mean age of 42....
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| Veröffentlicht in: | International Journal of Obesity 2004-09, Vol.28 (9), p.1174-1180 |
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| container_title | International Journal of Obesity |
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| creator | Valencia-Flores, M Rebollar, V Santiago, V Orea, A Rodríguez, C Resendiz, M Castaño, A Roblero, J Campos, R M Oseguera, J García-Ramos, G Bliwise, D L |
| description | OBJECTIVE:
To determine the point prevalence of pulmonary hypertension (PH) and its relationship with respiratory disturbances in obese patients living at moderate altitude.
SUBJECTS:
A total of 57 obese patients comprised the final sample and consisted of 34 women and 23 men, with a mean age of 42.7±12.1 ys and a mean body mass index (BMI) 47.1±10.6 kg/m
2
(range from 30.1 to 76.1). The mean living altitude was 2248.7 m, range 2100–2400 m above sea level.
MEASUREMENTS:
Doppler echocardiography, pulmonary function tests, arterial blood gas analysis, and polysomnography were performed.
RESULTS:
Data showed that 96.5% of the studied sample had daytime PH defined as calculated systolic pulmonary artery pressure (PSAP) >30 mmHg (mean PSAP=50, s.d.=13 mmHg). The severity of diurnal PH was found to be related to the presence of alveolar hypoventilation and BMI. The main risk factor for severity of diurnal PH was hypoventilation with a significant odds ratio (OR) 7.96, 95% CI 1.35–46.84, BMI was (OR 1.12, 95% CI 1.02–1.25) and apnea/hypopnea index was not a predictor of pulmonary hypertension severity (OR 0.99, 95% CI 0.97–1.02).
CONCLUSION:
We concluded that prevalence of diurnal PH is high in obese patients living at moderate altitude, and that hypoventilation is the main risk factor associated with the severity of pulmonary hypertension. |
| doi_str_mv | 10.1038/sj.ijo.0802726 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_journals_219203724</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A188449084</galeid><sourcerecordid>A188449084</sourcerecordid><originalsourceid>FETCH-LOGICAL-c455t-f4cfb096d253a2a5f025d5c2191847c02f81c4fb3771bf9f010601c472be7fa3</originalsourceid><addsrcrecordid>eNp1kU1r3DAQhk1pabZprz0W0dLevBnJlj-OIfQLAu0hdyPL0q6MLbkaOSG_oX-6s-zCtpCig2Dmed9h5s2ytxy2HIrmCsetG8MWGhC1qJ5lG17WVS7Ltn6ebaCAOgdZyYvsFeIIAFKCeJldcClEyYXcZL9_RnOvJuO1YcGyZZ3m4FV8ZPvHxcRkPLrgmfIDcwmZQgzaqXSoPbi0Z9Hg4qJKgRSDw7TGXpEVMudZ6A0athBtPGknd-_8jqnE5jAY0piJprjdnqkpubQO5nX2wqoJzZvTf5ndffl8d_Mtv_3x9fvN9W2uSylTbktte2irQchCCSUtCDlILXjLm7LWIGzDdWn7oq55b1sLHCqgSi16U1tVXGbvj7ZLDL9Wg6kbwxo9TezIQ0BRi5KgD0doR8fpnLchRaVnh7q75k1Tli00B2r7BEVvMLPTwRvrqP6P4NNfgr2h1fcYpvVwUXzSWceAGI3tluhmCqbj0B2S73DsKPnulDwJ3p22WvvZDGf8FDUBH0-AQq0mGykoh2eugqJtWyDu6sghtfzOxPN5_jP6D7EuyDc</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>219203724</pqid></control><display><type>article</type><title>Prevalence of pulmonary hypertension and its association with respiratory disturbances in obese patients living at moderately high altitude</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Nature Journals Online</source><source>SpringerLink Journals - AutoHoldings</source><creator>Valencia-Flores, M ; Rebollar, V ; Santiago, V ; Orea, A ; Rodríguez, C ; Resendiz, M ; Castaño, A ; Roblero, J ; Campos, R M ; Oseguera, J ; García-Ramos, G ; Bliwise, D L</creator><creatorcontrib>Valencia-Flores, M ; Rebollar, V ; Santiago, V ; Orea, A ; Rodríguez, C ; Resendiz, M ; Castaño, A ; Roblero, J ; Campos, R M ; Oseguera, J ; García-Ramos, G ; Bliwise, D L</creatorcontrib><description>OBJECTIVE:
To determine the point prevalence of pulmonary hypertension (PH) and its relationship with respiratory disturbances in obese patients living at moderate altitude.
SUBJECTS:
A total of 57 obese patients comprised the final sample and consisted of 34 women and 23 men, with a mean age of 42.7±12.1 ys and a mean body mass index (BMI) 47.1±10.6 kg/m
2
(range from 30.1 to 76.1). The mean living altitude was 2248.7 m, range 2100–2400 m above sea level.
MEASUREMENTS:
Doppler echocardiography, pulmonary function tests, arterial blood gas analysis, and polysomnography were performed.
RESULTS:
Data showed that 96.5% of the studied sample had daytime PH defined as calculated systolic pulmonary artery pressure (PSAP) >30 mmHg (mean PSAP=50, s.d.=13 mmHg). The severity of diurnal PH was found to be related to the presence of alveolar hypoventilation and BMI. The main risk factor for severity of diurnal PH was hypoventilation with a significant odds ratio (OR) 7.96, 95% CI 1.35–46.84, BMI was (OR 1.12, 95% CI 1.02–1.25) and apnea/hypopnea index was not a predictor of pulmonary hypertension severity (OR 0.99, 95% CI 0.97–1.02).
CONCLUSION:
We concluded that prevalence of diurnal PH is high in obese patients living at moderate altitude, and that hypoventilation is the main risk factor associated with the severity of pulmonary hypertension.</description><identifier>ISSN: 0307-0565</identifier><identifier>EISSN: 1476-5497</identifier><identifier>DOI: 10.1038/sj.ijo.0802726</identifier><identifier>PMID: 15224125</identifier><identifier>CODEN: IJOBDP</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Adult ; Altitude ; Anthropometry ; Biological and medical sciences ; Body mass index ; Circadian Rhythm ; Diabetes ; Doppler effect ; Echocardiography, Doppler ; Endocrinology ; Epidemiology ; Female ; Health Promotion and Disease Prevention ; Humans ; Hypertension ; Hypertension, Pulmonary - diagnostic imaging ; Hypertension, Pulmonary - etiology ; Hypoventilation ; Hypoventilation - complications ; Internal Medicine ; Male ; Medical sciences ; Medicine ; Medicine & Public Health ; Metabolic Diseases ; Middle Aged ; Obesity ; Obesity - complications ; Pneumology ; Polysomnography ; Public Health ; Pulmonary arteries ; Pulmonary hypertension ; Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases ; Respiratory function ; Respiratory system : syndromes and miscellaneous diseases ; Risk Factors ; Sea level ; Sleep apnea ; Sleep Apnea Syndromes - complications ; Veins & arteries</subject><ispartof>International Journal of Obesity, 2004-09, Vol.28 (9), p.1174-1180</ispartof><rights>Springer Nature Limited 2004</rights><rights>2005 INIST-CNRS</rights><rights>COPYRIGHT 2004 Nature Publishing Group</rights><rights>Copyright Nature Publishing Group Sep 2004</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c455t-f4cfb096d253a2a5f025d5c2191847c02f81c4fb3771bf9f010601c472be7fa3</citedby><cites>FETCH-LOGICAL-c455t-f4cfb096d253a2a5f025d5c2191847c02f81c4fb3771bf9f010601c472be7fa3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/sj.ijo.0802726$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/sj.ijo.0802726$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,777,781,27905,27906,41469,42538,51300</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16039990$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15224125$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Valencia-Flores, M</creatorcontrib><creatorcontrib>Rebollar, V</creatorcontrib><creatorcontrib>Santiago, V</creatorcontrib><creatorcontrib>Orea, A</creatorcontrib><creatorcontrib>Rodríguez, C</creatorcontrib><creatorcontrib>Resendiz, M</creatorcontrib><creatorcontrib>Castaño, A</creatorcontrib><creatorcontrib>Roblero, J</creatorcontrib><creatorcontrib>Campos, R M</creatorcontrib><creatorcontrib>Oseguera, J</creatorcontrib><creatorcontrib>García-Ramos, G</creatorcontrib><creatorcontrib>Bliwise, D L</creatorcontrib><title>Prevalence of pulmonary hypertension and its association with respiratory disturbances in obese patients living at moderately high altitude</title><title>International Journal of Obesity</title><addtitle>Int J Obes</addtitle><addtitle>Int J Obes Relat Metab Disord</addtitle><description>OBJECTIVE:
To determine the point prevalence of pulmonary hypertension (PH) and its relationship with respiratory disturbances in obese patients living at moderate altitude.
SUBJECTS:
A total of 57 obese patients comprised the final sample and consisted of 34 women and 23 men, with a mean age of 42.7±12.1 ys and a mean body mass index (BMI) 47.1±10.6 kg/m
2
(range from 30.1 to 76.1). The mean living altitude was 2248.7 m, range 2100–2400 m above sea level.
MEASUREMENTS:
Doppler echocardiography, pulmonary function tests, arterial blood gas analysis, and polysomnography were performed.
RESULTS:
Data showed that 96.5% of the studied sample had daytime PH defined as calculated systolic pulmonary artery pressure (PSAP) >30 mmHg (mean PSAP=50, s.d.=13 mmHg). The severity of diurnal PH was found to be related to the presence of alveolar hypoventilation and BMI. The main risk factor for severity of diurnal PH was hypoventilation with a significant odds ratio (OR) 7.96, 95% CI 1.35–46.84, BMI was (OR 1.12, 95% CI 1.02–1.25) and apnea/hypopnea index was not a predictor of pulmonary hypertension severity (OR 0.99, 95% CI 0.97–1.02).
CONCLUSION:
We concluded that prevalence of diurnal PH is high in obese patients living at moderate altitude, and that hypoventilation is the main risk factor associated with the severity of pulmonary hypertension.</description><subject>Adult</subject><subject>Altitude</subject><subject>Anthropometry</subject><subject>Biological and medical sciences</subject><subject>Body mass index</subject><subject>Circadian Rhythm</subject><subject>Diabetes</subject><subject>Doppler effect</subject><subject>Echocardiography, Doppler</subject><subject>Endocrinology</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Health Promotion and Disease Prevention</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Hypertension, Pulmonary - diagnostic imaging</subject><subject>Hypertension, Pulmonary - etiology</subject><subject>Hypoventilation</subject><subject>Hypoventilation - complications</subject><subject>Internal Medicine</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Metabolic Diseases</subject><subject>Middle Aged</subject><subject>Obesity</subject><subject>Obesity - complications</subject><subject>Pneumology</subject><subject>Polysomnography</subject><subject>Public Health</subject><subject>Pulmonary arteries</subject><subject>Pulmonary hypertension</subject><subject>Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases</subject><subject>Respiratory function</subject><subject>Respiratory system : syndromes and miscellaneous diseases</subject><subject>Risk Factors</subject><subject>Sea level</subject><subject>Sleep apnea</subject><subject>Sleep Apnea Syndromes - complications</subject><subject>Veins & arteries</subject><issn>0307-0565</issn><issn>1476-5497</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kU1r3DAQhk1pabZprz0W0dLevBnJlj-OIfQLAu0hdyPL0q6MLbkaOSG_oX-6s-zCtpCig2Dmed9h5s2ytxy2HIrmCsetG8MWGhC1qJ5lG17WVS7Ltn6ebaCAOgdZyYvsFeIIAFKCeJldcClEyYXcZL9_RnOvJuO1YcGyZZ3m4FV8ZPvHxcRkPLrgmfIDcwmZQgzaqXSoPbi0Z9Hg4qJKgRSDw7TGXpEVMudZ6A0athBtPGknd-_8jqnE5jAY0piJprjdnqkpubQO5nX2wqoJzZvTf5ndffl8d_Mtv_3x9fvN9W2uSylTbktte2irQchCCSUtCDlILXjLm7LWIGzDdWn7oq55b1sLHCqgSi16U1tVXGbvj7ZLDL9Wg6kbwxo9TezIQ0BRi5KgD0doR8fpnLchRaVnh7q75k1Tli00B2r7BEVvMLPTwRvrqP6P4NNfgr2h1fcYpvVwUXzSWceAGI3tluhmCqbj0B2S73DsKPnulDwJ3p22WvvZDGf8FDUBH0-AQq0mGykoh2eugqJtWyDu6sghtfzOxPN5_jP6D7EuyDc</recordid><startdate>20040901</startdate><enddate>20040901</enddate><creator>Valencia-Flores, M</creator><creator>Rebollar, V</creator><creator>Santiago, V</creator><creator>Orea, A</creator><creator>Rodríguez, C</creator><creator>Resendiz, M</creator><creator>Castaño, A</creator><creator>Roblero, J</creator><creator>Campos, R M</creator><creator>Oseguera, J</creator><creator>García-Ramos, G</creator><creator>Bliwise, D L</creator><general>Nature Publishing Group UK</general><general>Nature Publishing</general><general>Nature Publishing Group</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7T2</scope><scope>7TK</scope><scope>7TS</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope></search><sort><creationdate>20040901</creationdate><title>Prevalence of pulmonary hypertension and its association with respiratory disturbances in obese patients living at moderately high altitude</title><author>Valencia-Flores, M ; Rebollar, V ; Santiago, V ; Orea, A ; Rodríguez, C ; Resendiz, M ; Castaño, A ; Roblero, J ; Campos, R M ; Oseguera, J ; García-Ramos, G ; Bliwise, D L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c455t-f4cfb096d253a2a5f025d5c2191847c02f81c4fb3771bf9f010601c472be7fa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Adult</topic><topic>Altitude</topic><topic>Anthropometry</topic><topic>Biological and medical sciences</topic><topic>Body mass index</topic><topic>Circadian Rhythm</topic><topic>Diabetes</topic><topic>Doppler effect</topic><topic>Echocardiography, Doppler</topic><topic>Endocrinology</topic><topic>Epidemiology</topic><topic>Female</topic><topic>Health Promotion and Disease Prevention</topic><topic>Humans</topic><topic>Hypertension</topic><topic>Hypertension, Pulmonary - diagnostic imaging</topic><topic>Hypertension, Pulmonary - etiology</topic><topic>Hypoventilation</topic><topic>Hypoventilation - complications</topic><topic>Internal Medicine</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Metabolic Diseases</topic><topic>Middle Aged</topic><topic>Obesity</topic><topic>Obesity - complications</topic><topic>Pneumology</topic><topic>Polysomnography</topic><topic>Public Health</topic><topic>Pulmonary arteries</topic><topic>Pulmonary hypertension</topic><topic>Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases</topic><topic>Respiratory function</topic><topic>Respiratory system : syndromes and miscellaneous diseases</topic><topic>Risk Factors</topic><topic>Sea level</topic><topic>Sleep apnea</topic><topic>Sleep Apnea Syndromes - complications</topic><topic>Veins & arteries</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Valencia-Flores, M</creatorcontrib><creatorcontrib>Rebollar, V</creatorcontrib><creatorcontrib>Santiago, V</creatorcontrib><creatorcontrib>Orea, A</creatorcontrib><creatorcontrib>Rodríguez, C</creatorcontrib><creatorcontrib>Resendiz, M</creatorcontrib><creatorcontrib>Castaño, A</creatorcontrib><creatorcontrib>Roblero, J</creatorcontrib><creatorcontrib>Campos, R M</creatorcontrib><creatorcontrib>Oseguera, J</creatorcontrib><creatorcontrib>García-Ramos, G</creatorcontrib><creatorcontrib>Bliwise, D L</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Neurosciences Abstracts</collection><collection>Physical Education Index</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Psychology</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><jtitle>International Journal of Obesity</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Valencia-Flores, M</au><au>Rebollar, V</au><au>Santiago, V</au><au>Orea, A</au><au>Rodríguez, C</au><au>Resendiz, M</au><au>Castaño, A</au><au>Roblero, J</au><au>Campos, R M</au><au>Oseguera, J</au><au>García-Ramos, G</au><au>Bliwise, D L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevalence of pulmonary hypertension and its association with respiratory disturbances in obese patients living at moderately high altitude</atitle><jtitle>International Journal of Obesity</jtitle><stitle>Int J Obes</stitle><addtitle>Int J Obes Relat Metab Disord</addtitle><date>2004-09-01</date><risdate>2004</risdate><volume>28</volume><issue>9</issue><spage>1174</spage><epage>1180</epage><pages>1174-1180</pages><issn>0307-0565</issn><eissn>1476-5497</eissn><coden>IJOBDP</coden><abstract>OBJECTIVE:
To determine the point prevalence of pulmonary hypertension (PH) and its relationship with respiratory disturbances in obese patients living at moderate altitude.
SUBJECTS:
A total of 57 obese patients comprised the final sample and consisted of 34 women and 23 men, with a mean age of 42.7±12.1 ys and a mean body mass index (BMI) 47.1±10.6 kg/m
2
(range from 30.1 to 76.1). The mean living altitude was 2248.7 m, range 2100–2400 m above sea level.
MEASUREMENTS:
Doppler echocardiography, pulmonary function tests, arterial blood gas analysis, and polysomnography were performed.
RESULTS:
Data showed that 96.5% of the studied sample had daytime PH defined as calculated systolic pulmonary artery pressure (PSAP) >30 mmHg (mean PSAP=50, s.d.=13 mmHg). The severity of diurnal PH was found to be related to the presence of alveolar hypoventilation and BMI. The main risk factor for severity of diurnal PH was hypoventilation with a significant odds ratio (OR) 7.96, 95% CI 1.35–46.84, BMI was (OR 1.12, 95% CI 1.02–1.25) and apnea/hypopnea index was not a predictor of pulmonary hypertension severity (OR 0.99, 95% CI 0.97–1.02).
CONCLUSION:
We concluded that prevalence of diurnal PH is high in obese patients living at moderate altitude, and that hypoventilation is the main risk factor associated with the severity of pulmonary hypertension.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>15224125</pmid><doi>10.1038/sj.ijo.0802726</doi><tpages>7</tpages></addata></record> |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Nature Journals Online; SpringerLink Journals - AutoHoldings |
| subjects | Adult Altitude Anthropometry Biological and medical sciences Body mass index Circadian Rhythm Diabetes Doppler effect Echocardiography, Doppler Endocrinology Epidemiology Female Health Promotion and Disease Prevention Humans Hypertension Hypertension, Pulmonary - diagnostic imaging Hypertension, Pulmonary - etiology Hypoventilation Hypoventilation - complications Internal Medicine Male Medical sciences Medicine Medicine & Public Health Metabolic Diseases Middle Aged Obesity Obesity - complications Pneumology Polysomnography Public Health Pulmonary arteries Pulmonary hypertension Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases Respiratory function Respiratory system : syndromes and miscellaneous diseases Risk Factors Sea level Sleep apnea Sleep Apnea Syndromes - complications Veins & arteries |
| title | Prevalence of pulmonary hypertension and its association with respiratory disturbances in obese patients living at moderately high altitude |
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