sup 89^Zr-Bevacizumab PET of Early Antiangiogenic Tumor Response to Treatment with HSP90 Inhibitor NVP-AUY922

Angiogenesis is a critical step in tumor development, in which vascular endothelial growth factor (VEGF) is a key growth aspect. Heat shock protein 90 (HSP90), a molecular chaperone, is essential for the activity of key proteins involved in VEGF transcription. Currently, no biomarkers to predict the...

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Veröffentlicht in:	The Journal of nuclear medicine (1978) 2010-05, Vol.51 (5), p.761
Hauptverfasser:	Nagengast, Wouter B, de Korte, Maarten A, Munnink, Thijs H Oude, Timmer-Bosscha, Hetty, den Dunnen, Wifred F, Hollema, Harry, de Jong, Johan R, Jensen, Michael R, Quadt, Cornelia, Garcia-Echeverria, Carlos, van Dongen, Guus A M S, Hooge, Marjolijn N Lub-de, Schröder, Carolien P, de Vries, Elisabeth G E
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Animals Cancer Labeling Ovarian cancer Proteins Studies Vascular endothelial growth factor
Online-Zugang:	Volltext
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