Further development of the case-only design for assessing gene–environment interaction: evaluation of and adjustment for bias

Background The case-only study for investigating gene–environment interactions provides increased statistical efficiency over case-control analyses. This design has been criticized for being susceptible to bias arising from non-independence between the genetic and environmental factors in the popula...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	International journal of epidemiology 2004-10, Vol.33 (5), p.1014-1024
Hauptverfasser:	Gatto, Nicolle M, Campbell, Ulka B, Rundle, Andrew G, Ahsan, Habibul
Format:	Artikel
Sprache:	eng
Schlagworte:	Bias Bias (epidemiology) Case-Control Studies case-only design Disease - etiology environment Environmental Exposure - adverse effects epidemiological methods genes Genetic Predisposition to Disease Humans interaction Molecular Epidemiology - methods Research Design Risk Factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!