A Mouse Bone Marrow Dosimetry Model

Bone marrow is the primary dose-limiting organ in radioimmunotherapy. Athymic nude mouse models are used to guide radioimmunotherapy in humans. In the mouse, the dimensions of the marrow are comparable to the mean range of the beta particles for a wide variety of beta-emitting radionuclides, so loca...

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Veröffentlicht in:	The Journal of nuclear medicine (1978) 1998-07, Vol.39 (7), p.1243-1247
Hauptverfasser:	Muthuswamy, Moorthy S, Roberson, Peter L, Buchsbaum, Donald J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Bone Marrow - radiation effects Computer Simulation Dose-Response Relationship, Radiation Medical sciences Mice Mice, Nude Miscellaneous Models, Biological Radiation Dosage Radioimmunotherapy - adverse effects Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
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