Effects of HGF and KGF gene silencing on vascular endothelial growth factor and its receptors in rat ultraviolet radiation‑induced corneal neovascularization

Hepatocyte growth factor (HGF) and keratinocyte growth factor (KGF), two paracrine growth factors, modulate corneal epithelial cell metabolism, apoptosis and survival. Vascular endothelial growth factor (VEGF) serves as a proangiogenic factor in corneal neovascularization (CNV), which is a major cau...

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Veröffentlicht in:	International journal of molecular medicine 2019-04, Vol.43 (4), p.1888-1899
Hauptverfasser:	He, Min, Han, Tao, Wang, Yan, Wu, Yao-Hong, Qin, Wei-Shan, Du, Ling-Zhen, Zhao, Chang-Qing
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal experimentation Apoptosis Blindness Cell cycle Cell growth Deoxyribonucleic acid DNA Endothelial growth factors Experiments Gene silencing Genes Genetic aspects Genetic engineering Kinases Laboratory animals Neovascularization Novels Physiological aspects Radiation (Physics) Rodents Ultraviolet radiation Vascular endothelial growth factor Wound care Wound healing
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