Facile Synthesis of Orthogonally Protected Optically Pure Keto- and Diketopiperazine Building Blocks for Combinatorial Chemistry

A simple and convenient synthesis of orthogonally protected multi-tethered, optically pure 2-ketopiperazine and 2,5-diketopiperazine scaffolds for Fmoc and Boc combinatorial chemistry was achieved, starting from accessible chiral amino acid precursors, by sequentially utilizing reductive alkylation,...

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Veröffentlicht in:	International journal of peptide research and therapeutics 2008-06, Vol.14 (2), p.183-192
Hauptverfasser:	Gellerman, G., Hazan, E., Brider, T., Traube, T., Albeck, A., Shatzmiler, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Anatomy Biochemistry Biomedical and Life Sciences Biosynthesis Histology Life Sciences Molecular Medicine Morphology Peptides Pharmaceutical Sciences/Technology Pharmacology Pharmacology/Toxicology Polymer Sciences
Online-Zugang:	Volltext
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