Tracing cell fates in human colorectal tumors from somatic microsatellite mutations: Evidence of adenomas withs stem cell architecture

Occult aspects of tumor proliferation are likely recorded genetically as their microsatellite (MS) loci become polymorphic. However, MS mutations generated by division may also be eliminated with death as noncoding MS loci lack selective value. Therefore, highly polymorphic MS loci cannot exist unle...

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Veröffentlicht in:	The American journal of pathology 1998-10, Vol.153 (4), p.1189
Hauptverfasser:	Jen-Lan Tsao, Zhang, Jingsong, Salovaara, Reijo, Zhi-Hua, Li
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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