Clastogenic and Anticlastogenic Effect of the Essential Oil from Casearia sylvestris Swart
The essential oil composition obtained from the leaves of Casearia sylvestris has been investigated by GC and GC/MS. Thirty-seven compounds were identified in the oil. The major constituents of which were beta-caryophyllene (27.5%) and bicyclogermacrene (24.2%). The clastogenic and anticlastogenic e...
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| Veröffentlicht in: | The Journal of essential oil research 2007-07, Vol.19 (4), p.376-378 |
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| container_title | The Journal of essential oil research |
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| creator | Sousa, F.G Schneider, N.F.Z Mendes, C.E Moura, N.F. de Denardin, R.B.N Matuo, R Mantovani, M.S |
| description | The essential oil composition obtained from the leaves of Casearia sylvestris has been investigated by GC and GC/MS. Thirty-seven compounds were identified in the oil. The major constituents of which were beta-caryophyllene (27.5%) and bicyclogermacrene (24.2%). The clastogenic and anticlastogenic effect of the oil was tested by chromosome aberration in cells of tissue hepatoma of Rattus novergicus. The three different concentrations of C. sylvestris oil showed clastogenic effects. However, in the tests of anticlastogenicity, the same three concentrations showed protective activity when associated with ethyl methanesulfonate (EMS). |
| doi_str_mv | 10.1080/10412905.2007.9699309 |
| format | Article |
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Thirty-seven compounds were identified in the oil. The major constituents of which were beta-caryophyllene (27.5%) and bicyclogermacrene (24.2%). The clastogenic and anticlastogenic effect of the oil was tested by chromosome aberration in cells of tissue hepatoma of Rattus novergicus. The three different concentrations of C. sylvestris oil showed clastogenic effects. However, in the tests of anticlastogenicity, the same three concentrations showed protective activity when associated with ethyl methanesulfonate (EMS).</description><identifier>ISSN: 1041-2905</identifier><identifier>EISSN: 2163-8152</identifier><identifier>DOI: 10.1080/10412905.2007.9699309</identifier><language>eng</language><publisher>Carol Stream: Taylor & Francis Group</publisher><subject>anticlastogenic activity ; antimutagenic activity ; beta-caryophyllene ; bicyclogermacrene ; Casearia ; Casearia sylvestris ; cell lines ; chemical constituents of plants ; clastogenic activity ; essential oil composition ; essential oils ; ethyl methanesulfonate ; Flacourtiaceae ; gamma-terpinene ; gel permeation chromatography ; germacrene ; hepatoma ; leaves ; mutagenesis ; plant extracts ; protective effect ; rats ; Rattus norvegicus ; β-caryophyllene</subject><ispartof>The Journal of essential oil research, 2007-07, Vol.19 (4), p.376-378</ispartof><rights>Copyright Taylor & Francis Group, LLC 2007</rights><rights>Copyright Allured Publishing Corporation Jul/Aug 2007</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c361t-dddefd27c3f5e532e5316ca7e92deb4af4e285fd1a93ac76c025d95258c37ae53</citedby><cites>FETCH-LOGICAL-c361t-dddefd27c3f5e532e5316ca7e92deb4af4e285fd1a93ac76c025d95258c37ae53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids></links><search><creatorcontrib>Sousa, F.G</creatorcontrib><creatorcontrib>Schneider, N.F.Z</creatorcontrib><creatorcontrib>Mendes, C.E</creatorcontrib><creatorcontrib>Moura, N.F. de</creatorcontrib><creatorcontrib>Denardin, R.B.N</creatorcontrib><creatorcontrib>Matuo, R</creatorcontrib><creatorcontrib>Mantovani, M.S</creatorcontrib><title>Clastogenic and Anticlastogenic Effect of the Essential Oil from Casearia sylvestris Swart</title><title>The Journal of essential oil research</title><description>The essential oil composition obtained from the leaves of Casearia sylvestris has been investigated by GC and GC/MS. Thirty-seven compounds were identified in the oil. The major constituents of which were beta-caryophyllene (27.5%) and bicyclogermacrene (24.2%). The clastogenic and anticlastogenic effect of the oil was tested by chromosome aberration in cells of tissue hepatoma of Rattus novergicus. The three different concentrations of C. sylvestris oil showed clastogenic effects. However, in the tests of anticlastogenicity, the same three concentrations showed protective activity when associated with ethyl methanesulfonate (EMS).</description><subject>anticlastogenic activity</subject><subject>antimutagenic activity</subject><subject>beta-caryophyllene</subject><subject>bicyclogermacrene</subject><subject>Casearia</subject><subject>Casearia sylvestris</subject><subject>cell lines</subject><subject>chemical constituents of plants</subject><subject>clastogenic activity</subject><subject>essential oil composition</subject><subject>essential oils</subject><subject>ethyl methanesulfonate</subject><subject>Flacourtiaceae</subject><subject>gamma-terpinene</subject><subject>gel permeation chromatography</subject><subject>germacrene</subject><subject>hepatoma</subject><subject>leaves</subject><subject>mutagenesis</subject><subject>plant extracts</subject><subject>protective effect</subject><subject>rats</subject><subject>Rattus norvegicus</subject><subject>β-caryophyllene</subject><issn>1041-2905</issn><issn>2163-8152</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkMtKAzEUhoMoWKuPIAb3U3NpZiY7y1AvUOiiduMmHHOpU6aTmkwtfXtTpoI7F4dA-P4_Jx9Ct5SMKCnJAyVjyiQRI0ZIMZK5lJzIMzRgNOdZSQU7R4Mjkx2hS3QV45oQliJ0gN6rBmLnV7atNYbW4Enb1frP3dQ5qzvsHe4-LZ7GaBMADZ7XDXbBb3AF0UKoAcdD821jF-qIF3sI3TW6cNBEe3M6h2j5NH2rXrLZ_Pm1mswyzXPaZcYY6wwrNHfCCs7S0FxDYSUz9mMMbmxZKZyhIDnoIteECSMFE6XmBSR6iO773m3wX7u0gVr7XWjTk4rRUqb_s3GCRA_p4GMM1qltqDcQDooSdbSofi2qo0V1sphyj32ubp0PG9j70BjVwaHxwQVodR0V_6_irq9w4BWskh-1XDBCOUkZnqf5AYz-gyY</recordid><startdate>20070701</startdate><enddate>20070701</enddate><creator>Sousa, F.G</creator><creator>Schneider, N.F.Z</creator><creator>Mendes, C.E</creator><creator>Moura, N.F. de</creator><creator>Denardin, R.B.N</creator><creator>Matuo, R</creator><creator>Mantovani, M.S</creator><general>Taylor & Francis Group</general><general>Allured Publishing Corporation</general><scope>FBQ</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7XB</scope><scope>8AO</scope><scope>8FE</scope><scope>8FG</scope><scope>8FK</scope><scope>8G5</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>KB.</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PADUT</scope><scope>PDBOC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>S0X</scope></search><sort><creationdate>20070701</creationdate><title>Clastogenic and Anticlastogenic Effect of the Essential Oil from Casearia sylvestris Swart</title><author>Sousa, F.G ; Schneider, N.F.Z ; Mendes, C.E ; Moura, N.F. de ; Denardin, R.B.N ; Matuo, R ; Mantovani, M.S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c361t-dddefd27c3f5e532e5316ca7e92deb4af4e285fd1a93ac76c025d95258c37ae53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>anticlastogenic activity</topic><topic>antimutagenic activity</topic><topic>beta-caryophyllene</topic><topic>bicyclogermacrene</topic><topic>Casearia</topic><topic>Casearia sylvestris</topic><topic>cell lines</topic><topic>chemical constituents of plants</topic><topic>clastogenic activity</topic><topic>essential oil composition</topic><topic>essential oils</topic><topic>ethyl methanesulfonate</topic><topic>Flacourtiaceae</topic><topic>gamma-terpinene</topic><topic>gel permeation chromatography</topic><topic>germacrene</topic><topic>hepatoma</topic><topic>leaves</topic><topic>mutagenesis</topic><topic>plant extracts</topic><topic>protective effect</topic><topic>rats</topic><topic>Rattus norvegicus</topic><topic>β-caryophyllene</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sousa, F.G</creatorcontrib><creatorcontrib>Schneider, N.F.Z</creatorcontrib><creatorcontrib>Mendes, C.E</creatorcontrib><creatorcontrib>Moura, N.F. de</creatorcontrib><creatorcontrib>Denardin, R.B.N</creatorcontrib><creatorcontrib>Matuo, R</creatorcontrib><creatorcontrib>Mantovani, M.S</creatorcontrib><collection>AGRIS</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>Materials Science Database</collection><collection>ProQuest_Research Library</collection><collection>Research Library (Corporate)</collection><collection>Research Library China</collection><collection>Materials science collection</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><jtitle>The Journal of essential oil research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sousa, F.G</au><au>Schneider, N.F.Z</au><au>Mendes, C.E</au><au>Moura, N.F. de</au><au>Denardin, R.B.N</au><au>Matuo, R</au><au>Mantovani, M.S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clastogenic and Anticlastogenic Effect of the Essential Oil from Casearia sylvestris Swart</atitle><jtitle>The Journal of essential oil research</jtitle><date>2007-07-01</date><risdate>2007</risdate><volume>19</volume><issue>4</issue><spage>376</spage><epage>378</epage><pages>376-378</pages><issn>1041-2905</issn><eissn>2163-8152</eissn><abstract>The essential oil composition obtained from the leaves of Casearia sylvestris has been investigated by GC and GC/MS. Thirty-seven compounds were identified in the oil. The major constituents of which were beta-caryophyllene (27.5%) and bicyclogermacrene (24.2%). The clastogenic and anticlastogenic effect of the oil was tested by chromosome aberration in cells of tissue hepatoma of Rattus novergicus. The three different concentrations of C. sylvestris oil showed clastogenic effects. However, in the tests of anticlastogenicity, the same three concentrations showed protective activity when associated with ethyl methanesulfonate (EMS).</abstract><cop>Carol Stream</cop><pub>Taylor & Francis Group</pub><doi>10.1080/10412905.2007.9699309</doi><tpages>3</tpages></addata></record> |
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| subjects | anticlastogenic activity antimutagenic activity beta-caryophyllene bicyclogermacrene Casearia Casearia sylvestris cell lines chemical constituents of plants clastogenic activity essential oil composition essential oils ethyl methanesulfonate Flacourtiaceae gamma-terpinene gel permeation chromatography germacrene hepatoma leaves mutagenesis plant extracts protective effect rats Rattus norvegicus β-caryophyllene |
| title | Clastogenic and Anticlastogenic Effect of the Essential Oil from Casearia sylvestris Swart |
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