A lysosome-targeting dual-functional fluorescent probe for imaging intracellular viscosity and beta-amyloid
A lysosome-targeting dual-functional fluorescent probe was rationally designed and developed for imaging intracellular lysosomal viscosity and beta-amyloid. More importantly, the real-time tracking of the dynamic movement of lysosomes, as vesicle structures, has been achieved using Lyso-MC . A lysos...
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| Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2019-02, Vol.55 (18), p.2688-2691 |
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| container_title | Chemical communications (Cambridge, England) |
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| creator | Tan, Hui-ya Qiu, Yu-tai Sun, Han Yan, Jin-wu Zhang, Lei |
| description | A lysosome-targeting dual-functional fluorescent probe was rationally designed and developed for imaging intracellular lysosomal viscosity and beta-amyloid. More importantly, the real-time tracking of the dynamic movement of lysosomes, as vesicle structures, has been achieved using
Lyso-MC
.
A lysosome-targeting dual-functional fluorescent probe was rationally designed and developed for imaging intracellular lysosomal viscosity and beta-amyloid. |
| doi_str_mv | 10.1039/c9cc00113a |
| format | Article |
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Lyso-MC
.
A lysosome-targeting dual-functional fluorescent probe was rationally designed and developed for imaging intracellular lysosomal viscosity and beta-amyloid.</description><identifier>ISSN: 1359-7345</identifier><identifier>EISSN: 1364-548X</identifier><identifier>DOI: 10.1039/c9cc00113a</identifier><identifier>PMID: 30747206</identifier><language>eng</language><publisher>England: Royal Society of Chemistry</publisher><subject>Fluorescent indicators ; Lysosomes ; Viscosity</subject><ispartof>Chemical communications (Cambridge, England), 2019-02, Vol.55 (18), p.2688-2691</ispartof><rights>Copyright Royal Society of Chemistry 2019</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c337t-180cc4de43d311867c0cb903389cbc90a451f2db18d06ac2a5ad2c634ecd979f3</citedby><cites>FETCH-LOGICAL-c337t-180cc4de43d311867c0cb903389cbc90a451f2db18d06ac2a5ad2c634ecd979f3</cites><orcidid>0000-0002-2037-5008 ; 0000-0003-3014-0330</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30747206$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tan, Hui-ya</creatorcontrib><creatorcontrib>Qiu, Yu-tai</creatorcontrib><creatorcontrib>Sun, Han</creatorcontrib><creatorcontrib>Yan, Jin-wu</creatorcontrib><creatorcontrib>Zhang, Lei</creatorcontrib><title>A lysosome-targeting dual-functional fluorescent probe for imaging intracellular viscosity and beta-amyloid</title><title>Chemical communications (Cambridge, England)</title><addtitle>Chem Commun (Camb)</addtitle><description>A lysosome-targeting dual-functional fluorescent probe was rationally designed and developed for imaging intracellular lysosomal viscosity and beta-amyloid. More importantly, the real-time tracking of the dynamic movement of lysosomes, as vesicle structures, has been achieved using
Lyso-MC
.
A lysosome-targeting dual-functional fluorescent probe was rationally designed and developed for imaging intracellular lysosomal viscosity and beta-amyloid.</description><subject>Fluorescent indicators</subject><subject>Lysosomes</subject><subject>Viscosity</subject><issn>1359-7345</issn><issn>1364-548X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNpdkUtLxTAQhYMovjfulYAbEapJk7TN8lJ8geBGwV1JJ-mlmjaapML99-Y-VHA2MzAfhzNzEDqh5IoSJq9BAhBCKVNbaJ-ygmeCV6_by1nIrGRc7KGDEN5IKiqqXbTHSMnLnBT76H2G7SK44AaTReXnJvbjHOtJ2aybRoi9G5XFnZ2cNwHMGPGHd63BnfO4H9R8Sfdj9AqMtZNVHn_1AVzo4wKrUePWRJWpYWFdr4_QTqdsMMebfohebm-e6_vs8enuoZ49ZsBYGTNaEQCuDWeaUVoVJRBoJWGsktCCJIoL2uW6pZUmhYJcCaVzKBg3oGUpO3aILta6yernZEJshuQp-VOjcVNo8iRKeZEXIqHn_9A3N_l08ooSlSCirBJ1uabAuxC86ZoPn473i4aSZhlBU8u6XkUwS_DZRnJqB6N_0Z-fJ-B0DfgAv9u_DNk3G-SMeQ</recordid><startdate>20190226</startdate><enddate>20190226</enddate><creator>Tan, Hui-ya</creator><creator>Qiu, Yu-tai</creator><creator>Sun, Han</creator><creator>Yan, Jin-wu</creator><creator>Zhang, Lei</creator><general>Royal Society of Chemistry</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>L7M</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-2037-5008</orcidid><orcidid>https://orcid.org/0000-0003-3014-0330</orcidid></search><sort><creationdate>20190226</creationdate><title>A lysosome-targeting dual-functional fluorescent probe for imaging intracellular viscosity and beta-amyloid</title><author>Tan, Hui-ya ; Qiu, Yu-tai ; Sun, Han ; Yan, Jin-wu ; Zhang, Lei</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c337t-180cc4de43d311867c0cb903389cbc90a451f2db18d06ac2a5ad2c634ecd979f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Fluorescent indicators</topic><topic>Lysosomes</topic><topic>Viscosity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tan, Hui-ya</creatorcontrib><creatorcontrib>Qiu, Yu-tai</creatorcontrib><creatorcontrib>Sun, Han</creatorcontrib><creatorcontrib>Yan, Jin-wu</creatorcontrib><creatorcontrib>Zhang, Lei</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>MEDLINE - Academic</collection><jtitle>Chemical communications (Cambridge, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tan, Hui-ya</au><au>Qiu, Yu-tai</au><au>Sun, Han</au><au>Yan, Jin-wu</au><au>Zhang, Lei</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A lysosome-targeting dual-functional fluorescent probe for imaging intracellular viscosity and beta-amyloid</atitle><jtitle>Chemical communications (Cambridge, England)</jtitle><addtitle>Chem Commun (Camb)</addtitle><date>2019-02-26</date><risdate>2019</risdate><volume>55</volume><issue>18</issue><spage>2688</spage><epage>2691</epage><pages>2688-2691</pages><issn>1359-7345</issn><eissn>1364-548X</eissn><abstract>A lysosome-targeting dual-functional fluorescent probe was rationally designed and developed for imaging intracellular lysosomal viscosity and beta-amyloid. More importantly, the real-time tracking of the dynamic movement of lysosomes, as vesicle structures, has been achieved using
Lyso-MC
.
A lysosome-targeting dual-functional fluorescent probe was rationally designed and developed for imaging intracellular lysosomal viscosity and beta-amyloid.</abstract><cop>England</cop><pub>Royal Society of Chemistry</pub><pmid>30747206</pmid><doi>10.1039/c9cc00113a</doi><tpages>4</tpages><orcidid>https://orcid.org/0000-0002-2037-5008</orcidid><orcidid>https://orcid.org/0000-0003-3014-0330</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1359-7345 |
| ispartof | Chemical communications (Cambridge, England), 2019-02, Vol.55 (18), p.2688-2691 |
| issn | 1359-7345 1364-548X |
| language | eng |
| recordid | cdi_proquest_journals_2185850578 |
| source | Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Fluorescent indicators Lysosomes Viscosity |
| title | A lysosome-targeting dual-functional fluorescent probe for imaging intracellular viscosity and beta-amyloid |
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