Interactions of Pluronic F127 in Rhodamine B Dye and Effects of Inorganic Cations through Fluorescence Data

Non-ionic surfactant block copolymer of polypropylene glycol flanked by two blocks of polyethylene glycol known as pluronic. Pluronic F127 or poloxamer 407 is used to improve the solubility and enhance the bioavilability of many drugs. The interactions of pluronic F127 was studied in Rhodamine B dye...

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Veröffentlicht in:Russian Journal of Physical Chemistry A 2018-12, Vol.92 (13), p.2817-2826
Hauptverfasser: Jenif Dsouza Antonisamy, Sasmita Dash
Format: Artikel
Sprache:eng
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Zusammenfassung:Non-ionic surfactant block copolymer of polypropylene glycol flanked by two blocks of polyethylene glycol known as pluronic. Pluronic F127 or poloxamer 407 is used to improve the solubility and enhance the bioavilability of many drugs. The interactions of pluronic F127 was studied in Rhodamine B dye and effects of inorganic cations through fluorescence data were observed. Fluorescence quenching were studied by series cations of salts viz CdSO 4 , MnSO 4 , ZnSO 4 , FeSO 4 , CuSO 4 in the above system. Cu 2+ was found to be extremely efficient quencher, Cd 2+ and Fe 2+ were moderate quenchers. Apart from fluorescence, lifetime, DLS, and SEM were used as characterization for the above study.
ISSN:0036-0244
1531-863X
DOI:10.1134/S0036024418130022