A Precisely Designed Immunotoxin Against VCAM1 Consisting of a Humanized Antibody Variable Domain Fused to Granzyme: An In Silico Approach

Atherosclerosis is a complex disease related to cardiovascular disorders and is one of the most considerable causes of mortality worldwide. It has been shown that the immune system plays a pivotal role in generating atherosclerosis plaques. The atherosclerosis plaques form via activation of endothel...

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Veröffentlicht in:	International journal of peptide research and therapeutics 2020-03, Vol.26 (1), p.129-137
Hauptverfasser:	Ganji, Mahmoud, Khalili, Saeed, Mard-Soltani, Maysam, Khalesi, Bahman, Karkhah, Ahmad, Amani, Jafar
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Anatomy Arteriosclerosis Atherosclerosis Biochemistry Biological properties Biomedical and Life Sciences Cancer Cell adhesion molecules Computer programs Design Drug development Endothelial cells Histology Homology Immune system Life Sciences Molecular Medicine Morphology Pharmaceutical Sciences/Technology Pharmacology/Toxicology Plaques Polymer Sciences
Online-Zugang:	Volltext
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