Immortalization of normal adult human middle ear epithelial cells using retrovirus containing the E6/E7 genes of human papillomarvirus type 16

A human middle ear epithelial cell line (HMEEC-1) was established using human papillomavirus E6/E7 genes. HMEEC-1 has remained morphologically and phenotypically stable, even after 50 passages. The cells are anchorage-dependent and nontumorigenic when injected into nude mice. This cell line thus pro...

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Veröffentlicht in:	Annals of otology, rhinology & laryngology rhinology & laryngology, 2002-06, Vol.111 (6), p.507
Hauptverfasser:	Young-Myoung, Chun, Sung-Kyun Moon, Brackmann, Derald E, Lee, Haa-Yung
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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