Blood Transcriptomics Analysis of Fish Exposed to Perfluoro Alkyls Substances: Assessment of a Non-Lethal Sampling Technique for Advancing Aquatic Toxicology Research

In contrast to mammals, the blood from other vertebrates such as fish contains nucleated red cells. Using a fathead minnow (Pimephales promelas) oligonucleotide microarray, we compared altered transcripts in the liver and whole blood after exposure to environmentally relevant concentrations of perfl...

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Veröffentlicht in:	Environmental science & technology 2019-02, Vol.53 (3), p.1441-1452
Hauptverfasser:	Rodríguez-Jorquera, Ignacio A, Colli-Dula, R. Cristina, Kroll, Kevin, Jayasinghe, B. Sumith, Parachu Marco, Maria V, Silva-Sanchez, Cecilia, Toor, Gurpal S, Denslow, Nancy D
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood Cholesterol Contaminants Deoxyribonucleic acid Design of experiments Disruption DNA DNA fingerprinting DNA microarrays Endangered species Endocrine disruptors Estrogens Experimental design Exposure Gene expression Genes Genomics Immune system Lipid metabolism Liver Mammals Metabolism Mitochondria Oligonucleotides Perfluoro compounds Perfluoroalkyl & polyfluoroalkyl substances Perfluorooctane sulfonic acid Perfluorooctanoic acid Pimephales promelas Pollution effects Polymerase chain reaction Receptor density Sampling Thyroid Tissues Toxicology Vertebrates Vitellogenin Wildlife Xenoestrogens
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