[3H]GR113808 binding to serotonin 5-HT4 receptors in the postmortem neocortex of Alzheimer disease: a clinicopathological study

Abnormalities in neural transmission of serotonin (5-HT) may play a role in both cognitive and neuropsychiatric features of Alzheimer disease (AD). We measured 5-HT4 receptors in the postmortem frontal and temporal cortex of 34 AD subjects and 15 controls by radioligand binding with [3H]GR113808. Re...

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Veröffentlicht in:Journal of Neural Transmission 2003-07, Vol.110 (7), p.779-788
Hauptverfasser: LAI, M. K, TSANG, S. W, FRANCIS, P. T, ESIRI, M. M, HOPE, T, LAI, O. F, SPENCE, I, CHEN, C. P
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Sprache:eng
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