Efficacy and tolerability of entacapone in patients with Parkinson's disease treated with levodopa plus a dopamine agonist and experiencing wearing-off motor fluctuations. A randomized, double-blind, multicentre study

The efficacy and tolerability of entacapone was investigated in a randomized, double-blind, placebo-controlled, 3-month study of 162 patients with Parkinson's disease (PD) treated with levodopa and a dopamine agonist and experiencing wearing-off motor fluctuations. Patients were randomized in a...

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Veröffentlicht in:	Journal of Neural Transmission 2003-03, Vol.110 (3), p.239-251
Hauptverfasser:	FENELON, G, GIMENEZ-ROLDAN, S, MONTASTRUC, J. L, BERMEJO, F, DURIF, F, BOURDEIX, I, PERE, J.-J, GALIANO, L, SCHADRACK, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anticonvulsants. Antiepileptics. Antiparkinson agents Biological and medical sciences Catechols - adverse effects Catechols - therapeutic use Dopamine Agonists - therapeutic use Double-Blind Method Drug Therapy, Combination Female Humans Levodopa - therapeutic use Male Medical sciences Middle Aged Neuropharmacology Nitriles Parkinson Disease - drug therapy Parkinson Disease - physiopathology Parkinson Disease - psychology Pharmacology. Drug treatments Prospective Studies
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