Design and Synthesis of Novel C4‐Linked Substituted 2H‐Chromen‐2‐one‐hypoxanthine Hybrids as Potential Antimicrobial Agents: An Approach to Molecular Docking Studies

We present here design and synthesis of very efficient, high‐yielded and simple approach of a series of C4‐linked coumarin–hypoxanthine pharmacophores 1(a–j) with moderate to excellent in vitro antimicrobial activity. According to earlier studies, potential modification at C4‐position of coumarin ri...

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Veröffentlicht in:	Journal of heterocyclic chemistry 2019-02, Vol.56 (2), p.579-588
Hauptverfasser:	Naik, Soniya D., Hosamani, Kallappa M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiinfectives and antibacterials Antimicrobial agents Biomolecules Chemical synthesis Coumarin Excretion Hybrids Hypoxanthine Metabolism Molecular docking Pharmacology
Online-Zugang:	Volltext
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