Interaction of NKX3.1 and SELENOP genotype with prostate cancer recurrence

Background: NKX3.1 is a tumor suppressor frequently lost in prostate cancer. Previous studies by others indicated that the risks associated with reduced NKX3.1 levels can be enhanced by anti‐oxidant supplementation. Selenium is an essential component of several proteins with anti‐oxidant functions a...

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Veröffentlicht in:	The Prostate 2019-04, Vol.79 (5), p.462-467
Hauptverfasser:	Donadio, Janaina L. S., Liu, Li, Freeman, Vincent L., Ekoue, Dede N., Diamond, Alan M., Bermano, Giovanna
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer surgery Cohort Studies Gene polymorphism Genetic Predisposition to Disease Genotype Genotype & phenotype Homeodomain Proteins - genetics Humans Kallikreins - blood Male Middle Aged Neoplasm Recurrence, Local - blood Neoplasm Recurrence, Local - genetics Neoplasm Recurrence, Local - pathology Nkx3.1 protein Polymorphism, Single Nucleotide Prospective Studies Prostate cancer Prostate-Specific Antigen - blood Prostatectomy Prostatic Neoplasms - blood Prostatic Neoplasms - genetics Prostatic Neoplasms - pathology Prostatic Neoplasms - surgery Selenium Selenoprotein P - genetics selenoproteins Supplements Transcription Factors - genetics Tumor suppressor genes Urological surgery
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