Influence of [alpha]-tocopherol on the levels of serum anti-oxLDL antibodies
Purpose - This paper aims to evaluate the association between the α-tocopherol with the levels of serum anti-oxLDL autoantibodies and the risk markers for cardiovascular disease. Design/methodology/approach - A normolipidemic control group (n=30) and a hypercholesterolemic group (n=33) were used. Pl...
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| Veröffentlicht in: | Nutrition and food science 2009-01, Vol.39 (1), p.50 |
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| creator | Elaine A.A. Sanibal Nágila R.T. Damasceno Gidlund, Magnus A Elizabeth A.F.S. Torres |
| description | Purpose - This paper aims to evaluate the association between the α-tocopherol with the levels of serum anti-oxLDL autoantibodies and the risk markers for cardiovascular disease. Design/methodology/approach - A normolipidemic control group (n=30) and a hypercholesterolemic group (n=33) were used. Plasma lipid profile (colorimetric method), anti-oxLDL autoantibodies (ELISA) and α-tocopherol (HPLC) were analysed. Findings - The α-tocopherol (ß=-0.714; p=0.001) is negatively associated with anti-oxLDL autoantibodies in serum and with other risk markers for cardiovascular disease (BMI, WC, total cholesterol, LDL-c) and positively associated with HDL-c. Originality/value - Oxidized low density lipoprotein (oxLDL) and their autoantibodies are increased in subjects with hypercholesterolemia. The α-tocopherol can influence the levels of serum anti-oxLDL autoantibodies. |
| doi_str_mv | 10.1108/00346650910930824 |
| format | Article |
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Findings - The α-tocopherol (ß=-0.714; p=0.001) is negatively associated with anti-oxLDL autoantibodies in serum and with other risk markers for cardiovascular disease (BMI, WC, total cholesterol, LDL-c) and positively associated with HDL-c. Originality/value - Oxidized low density lipoprotein (oxLDL) and their autoantibodies are increased in subjects with hypercholesterolemia. The α-tocopherol can influence the levels of serum anti-oxLDL autoantibodies.</abstract><cop>Bradford</cop><pub>Emerald Group Publishing Limited</pub><doi>10.1108/00346650910930824</doi></addata></record> |
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| source | Emerald Journals |
| subjects | Cardiology Cardiovascular disease Cardiovascular diseases Cholesterol Diet Free radicals Hypothyroidism Immune system Kidney diseases Liquid chromatography Nutrition Protease inhibitors Research methodology Society |
| title | Influence of [alpha]-tocopherol on the levels of serum anti-oxLDL antibodies |
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