Agonist-specific activation of the [beta]2-adrenoceptor/Gs-protein and [beta]2-adrenoceptor/Gi-protein pathway in adult rat ventricular cardiomyocytes

In rat ventricular cardiomyocytes beta2-adrenoceptors (AR) couple to Gs- and Gi-protein, and evidence has accumulated that beta2-AR agonists can differentially activate either Gs- or Gs- and Gi-protein. In this study, in isolated adult rat ventricular cardiomyocytes, we assessed the effects of pertu...

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Veröffentlicht in:	British journal of pharmacology 2006-04, Vol.147 (7), p.714
Hauptverfasser:	Pönicke, Klaus, Gröner, Ferdinand, Heinroth-Hoffmann, Ingrid, Otto-Erich Brodde
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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