Clonidine-induced nitric oxide-dependent vasorelaxation mediated by endothelial [alpha]2-adrenoceptor activation

1. To assess the involvement of endothelial alpha(2)-adrenoceptors in the clonidine-induced vasodilatation, the mesenteric artery of Sprague Dawley rats was cannulated and perfused with Tyrode solution (2 ml min(-1)). We measured perfusion pressure, nitric oxide (NO) in the perfusate using chemilumi...

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Veröffentlicht in:	British journal of pharmacology 2001-11, Vol.134 (5), p.957
Hauptverfasser:	Figueroa, Xavier F, Poblete, M Inés, Boric, Mauricio P, Mendizábal, Victoria E, Adler-Graschinsky, Edda, J Pablo Huidobro-Toro
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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