Once-Weekly Epoetin-Beta Improves Hemoglobin Levels in Cancer Patients with Chemotherapy-Induced Anemia: A Randomized, Double-Blind, Dose-Finding Study

Objective: To determine a recommended dose of once-weekly epoetin-beta administration for anemic cancer patients receiving myelosuppressive chemotherapy, we conducted a multicenter, randomized, double-blind trial. Methods: A total of 86 patients with malignant lymphoma or lung cancer who received ch...

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Veröffentlicht in:	Japanese journal of clinical oncology 2006-10, Vol.36 (10), p.655-661
Hauptverfasser:	Morishima, Yasuo, Ogura, Michinori, Yoneda, Shuichi, Sakai, Hiroshi, Tobinai, Kensei, Nishiwaki, Yutaka, Minami, Hironobu, Hotta, Tomomitsu, Ezaki, Kohji, Ohe, Yuichiro, Yokoyama, Akira, Tsuboi, Masahiro, Mori, Kiyoshi, Watanabe, Koshiro, Ohashi, Yasuo, Hirashima, Kunitake, Saijo, Nagahiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anemia - chemically induced Anemia - drug therapy Anemia - therapy Anthracyclines - administration & dosage Antineoplastic Combined Chemotherapy Protocols - adverse effects Bridged-Ring Compounds - administration & dosage chemotherapy-induced anemia Dose-Response Relationship, Drug Double-Blind Method Drug Administration Schedule Erythrocyte Transfusion erythropoietin Erythropoietin - administration & dosage Erythropoietin - adverse effects Female Hemoglobins - analysis Humans Leukopenia - chemically induced lung cancer Lung Neoplasms - blood Lung Neoplasms - drug therapy Lymphoma - blood Lymphoma - drug therapy Male malignant lymphoma Middle Aged Platinum Compounds - administration & dosage Quality of Life Recombinant Proteins Taxoids - administration & dosage
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