Prospective, Randomized, Double-Blind Study of the Efficacy and Tolerability of the Extended-Release Formulations of Oxybutynin and Tolterodine for Overactive Bladder: Results of the OPERA Trial

To compare the efficacy and tolerability of extended-release formulations of oxybutynin chloride and tolterodine tartrate in women with overactive bladder. The OPERA (Overactive bladder: Performance of Extended Release Agents) trial was a randomized, double-blind, active-control study performed at 7...

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Veröffentlicht in:	Mayo Clinic proceedings 2003-06, Vol.78 (6), p.687-695
Hauptverfasser:	Diokno, Ananias C., Appell, Rodney A., Sand, Peter K., Dmochowski, Roger R., Gburek, Bernard M., Klimberg, Ira W., Kell, Sherron H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Aged Benzhydryl Compounds - administration & dosage Benzhydryl Compounds - adverse effects Biological and medical sciences Constipation - chemically induced Cresols - administration & dosage Cresols - adverse effects Delayed-Action Preparations Diarrhea - chemically induced Double-Blind Method Female Headache - chemically induced Humans Mandelic Acids - administration & dosage Mandelic Acids - adverse effects Medical sciences Middle Aged Muscarinic Antagonists - administration & dosage Muscarinic Antagonists - adverse effects Pharmacology. Drug treatments Phenylpropanolamine Prospective Studies Salivation - drug effects Tartrates - administration & dosage Tartrates - adverse effects Tolterodine Tartrate Treatment Outcome Urinary Incontinence - drug therapy Urinary Incontinence - physiopathology Urinary system Urinary Tract Infections - chemically induced Urination - drug effects
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