Ca V 2.1 α 1 Subunit Expression Regulates Presynaptic Ca V 2.1 Abundance and Synaptic Strength at a Central Synapse

The abundance of presynaptic Ca 2 voltage-gated Ca channels (Ca 2) at mammalian active zones (AZs) regulates the efficacy of synaptic transmission. It is proposed that presynaptic Ca 2 levels are saturated in AZs due to a finite number of slots that set Ca 2 subtype abundance and that Ca 2.1 cannot...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neuron (Cambridge, Mass.) Mass.), 2019-01, Vol.101 (2), p.260
Hauptverfasser:	Lübbert, Matthias, Goral, R Oliver, Keine, Christian, Thomas, Connon, Guerrero-Given, Debbie, Putzke, Travis, Satterfield, Rachel, Kamasawa, Naomi, Young, Jr, Samuel M
Format:	Artikel
Sprache:	eng
Schlagworte:	Abundance Animals Animals, Newborn Biophysics Brain Stem - cytology Cadmium Chloride - pharmacology Calcium - metabolism Calcium Channel Blockers - pharmacology Calcium channels Calcium channels (voltage-gated) Calcium Channels, N-Type - genetics Calcium Channels, N-Type - metabolism Developmental stages Electric Stimulation Female Green Fluorescent Proteins - genetics Green Fluorescent Proteins - metabolism Male Mice Mice, Inbred C57BL Mice, Transgenic Neurotransmitter Agents - metabolism Presynaptic Terminals - physiology Presynaptic Terminals - ultrastructure Synapses Synapses - physiology Synapses - ultrastructure Synaptic strength Synaptic transmission Synaptic Transmission - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!