Lipoxygenases and other stress response proteins in experimental models of Alzheimer’s disease. Searching for promising targets in neuroprotection

It is proposed that oxidative stress, amyloid β oligomers (AβO) and alterations of ceramide metabolism/level may play a crucial role in pathogenesis and in mechanism of Alzheimer’s disease (AD). This study focused on the expression of genes encoded lipoxygenases and other prooxidative/antioxidative...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Folia neuropathologica 2018-01, Vol.56 (3), p.259
Hauptverfasser:	Wojtowicz, S, Cieslik, M, Czubowicz, K, Strosznajder, JB
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Amyloid Amyloid precursor protein Animal models Apoptosis Apoptosis-inducing factor Ceramide Enzymes Gene expression Mitochondria Mutation Neuroprotection Nitric oxide Nitric-oxide synthase Oxidative stress Pheochromocytoma cells Secretase Sirtuins Superoxide dismutase Toxicity Transcription Transgenic mice β-Site APP-cleaving enzyme 1
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!