Polymorphic variations in the neurogenic differentiation-1, neurogenin-3, and hepatocyte nuclear factor-1[alpha] genes contribute to glucose intolerance in a South Indian population.(Brief Genetics Report)

The neurogenic differentiation-1 (NEUROD1), neurogenin-3 (NEUROG3), and hepatic nuclear factor-1alpha (TCF1) genes are interacting transcription factors implicated in controlling islet cell development and insulin secretion. Polymorphisms of these genes (Ala45Thr [NEUROD1], Ser199Phe [NEUROG3], and...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2004-08, Vol.53 (8), p.2122
Hauptverfasser:	Jackson, Alan E, Cassell, Paul G, North, Bernard V, Vijayaraghavan, Shanti, Gelding, Susan V, Ramachandran, Ambady, Snehalatha, Chamukuttan, Hitman, Graham A
Format:	Artikel
Sprache:	eng
Schlagworte:	Causes of Diabetes Fasting Genes Genetic aspects Genotype & phenotype Glucose Glucose intolerance Insulin Mutation Peptides Polymorphism Regression analysis Risk factors Transcription factors Type 2 diabetes
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!