Control and function of sebaceous glands
A. J. Thody and S. Shuster Department of Dermatology, University of Newcastle upon Tyne, United Kingdom. This review describes the various types of sebaceous glands, their locations, and where possible their different functions. All sebaceous glands are similar in structure and secrete sebum by a ho...
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| Veröffentlicht in: | Physiological reviews 1989-04, Vol.69 (2), p.383-416 |
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| container_title | Physiological reviews |
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| creator | Thody, A. J Shuster, S |
| description | A. J. Thody and S. Shuster
Department of Dermatology, University of Newcastle upon Tyne, United Kingdom.
This review describes the various types of sebaceous glands, their
locations, and where possible their different functions. All sebaceous
glands are similar in structure and secrete sebum by a holocrine process.
However, the nature of this secretion and the regulation of the secretory
process seem to differ among the various types of glands. Methods for
measuring sebum secretion and assessing sebaceous gland activity are also
described. The area of major interest during the last 20 years has
undoubtedly been the mechanisms that control sebaceous gland function. Most
studies have focused on the endocrine control and in particular on the role
of androgens and pituitary hormones, although evidence suggests that
nonendocrine factors may also be important. However, many questions remain
and during the next few years attention will certainly be given to the role
of retinoids and their mode of action in the treatment of acne. |
| doi_str_mv | 10.1152/physrev.1989.69.2.383 |
| format | Article |
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Department of Dermatology, University of Newcastle upon Tyne, United Kingdom.
This review describes the various types of sebaceous glands, their
locations, and where possible their different functions. All sebaceous
glands are similar in structure and secrete sebum by a holocrine process.
However, the nature of this secretion and the regulation of the secretory
process seem to differ among the various types of glands. Methods for
measuring sebum secretion and assessing sebaceous gland activity are also
described. The area of major interest during the last 20 years has
undoubtedly been the mechanisms that control sebaceous gland function. Most
studies have focused on the endocrine control and in particular on the role
of androgens and pituitary hormones, although evidence suggests that
nonendocrine factors may also be important. However, many questions remain
and during the next few years attention will certainly be given to the role
of retinoids and their mode of action in the treatment of acne.</description><identifier>ISSN: 0031-9333</identifier><identifier>EISSN: 1522-1210</identifier><identifier>DOI: 10.1152/physrev.1989.69.2.383</identifier><identifier>PMID: 2648418</identifier><identifier>CODEN: PHREA7</identifier><language>eng</language><publisher>Bethesda, MD: Am Physiological Soc</publisher><subject>Anatomy & physiology ; Animals ; Biological and medical sciences ; Fundamental and applied biological sciences. Psychology ; Hormones - physiology ; Humans ; Lipids - biosynthesis ; Sebaceous Glands - physiology ; Sebaceous Glands - secretion ; Sebum - secretion ; Vertebrates: skin, associated glands, phaneres, light organs, various exocrine glands (salt gland, uropygial gland...), adipose tissue, connective tissue</subject><ispartof>Physiological reviews, 1989-04, Vol.69 (2), p.383-416</ispartof><rights>1990 INIST-CNRS</rights><rights>Copyright American Physiological Society Apr 1989</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c462t-30a0dfcf4cba61d3db99a15ba5f9870747e12ce4a82ef40e43d712b30562c2be3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=6966533$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2648418$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Thody, A. J</creatorcontrib><creatorcontrib>Shuster, S</creatorcontrib><title>Control and function of sebaceous glands</title><title>Physiological reviews</title><addtitle>Physiol Rev</addtitle><description>A. J. Thody and S. Shuster
Department of Dermatology, University of Newcastle upon Tyne, United Kingdom.
This review describes the various types of sebaceous glands, their
locations, and where possible their different functions. All sebaceous
glands are similar in structure and secrete sebum by a holocrine process.
However, the nature of this secretion and the regulation of the secretory
process seem to differ among the various types of glands. Methods for
measuring sebum secretion and assessing sebaceous gland activity are also
described. The area of major interest during the last 20 years has
undoubtedly been the mechanisms that control sebaceous gland function. Most
studies have focused on the endocrine control and in particular on the role
of androgens and pituitary hormones, although evidence suggests that
nonendocrine factors may also be important. However, many questions remain
and during the next few years attention will certainly be given to the role
of retinoids and their mode of action in the treatment of acne.</description><subject>Anatomy & physiology</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Hormones - physiology</subject><subject>Humans</subject><subject>Lipids - biosynthesis</subject><subject>Sebaceous Glands - physiology</subject><subject>Sebaceous Glands - secretion</subject><subject>Sebum - secretion</subject><subject>Vertebrates: skin, associated glands, phaneres, light organs, various exocrine glands (salt gland, uropygial gland...), adipose tissue, connective tissue</subject><issn>0031-9333</issn><issn>1522-1210</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkN1LwzAUxYMoc07_hEEREUFa893mUYZfMPBFn0OaJltH18xkVfbfm7rSB5_uwzn3nHt_AMwRzBBi-GG3PgRvvjMkCpFxkeGMFOQETKOGU4QRPAVTCAlKBSHkHFyEsIEQMsbZBEwwpwVFxRTcLVy7965JVFsltmv1vnZt4mwSTKm0cV1IVk3UwiU4s6oJ5mqYM_D5_PSxeE2X7y9vi8dlqinH-5RABSurLdWl4qgiVSmEQqxUzIoihznNDcLaUFVgYyk0lFQ5wiWBjGONS0Nm4PaYu_PuqzNhL7d10KaJR_TXyLwQSPD40wxc_zNuXOfbeJvEKL4HYZ5HEzuatHch4rJy5-ut8geJoOwxygGj7DFKLiSWEWPcmw_hXbk11bg1cIv6zaCroFVjvWp1HUYbF5wz0sfcH23rerX-qb35q6td41aHsXks_QWAAYuD</recordid><startdate>19890401</startdate><enddate>19890401</enddate><creator>Thody, A. J</creator><creator>Shuster, S</creator><general>Am Physiological Soc</general><general>American Physiological Society</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7TK</scope><scope>7TS</scope><scope>7X8</scope></search><sort><creationdate>19890401</creationdate><title>Control and function of sebaceous glands</title><author>Thody, A. J ; Shuster, S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c462t-30a0dfcf4cba61d3db99a15ba5f9870747e12ce4a82ef40e43d712b30562c2be3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>Anatomy & physiology</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Hormones - physiology</topic><topic>Humans</topic><topic>Lipids - biosynthesis</topic><topic>Sebaceous Glands - physiology</topic><topic>Sebaceous Glands - secretion</topic><topic>Sebum - secretion</topic><topic>Vertebrates: skin, associated glands, phaneres, light organs, various exocrine glands (salt gland, uropygial gland...), adipose tissue, connective tissue</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Thody, A. J</creatorcontrib><creatorcontrib>Shuster, S</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Physical Education Index</collection><collection>MEDLINE - Academic</collection><jtitle>Physiological reviews</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Thody, A. J</au><au>Shuster, S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Control and function of sebaceous glands</atitle><jtitle>Physiological reviews</jtitle><addtitle>Physiol Rev</addtitle><date>1989-04-01</date><risdate>1989</risdate><volume>69</volume><issue>2</issue><spage>383</spage><epage>416</epage><pages>383-416</pages><issn>0031-9333</issn><eissn>1522-1210</eissn><coden>PHREA7</coden><abstract>A. J. Thody and S. Shuster
Department of Dermatology, University of Newcastle upon Tyne, United Kingdom.
This review describes the various types of sebaceous glands, their
locations, and where possible their different functions. All sebaceous
glands are similar in structure and secrete sebum by a holocrine process.
However, the nature of this secretion and the regulation of the secretory
process seem to differ among the various types of glands. Methods for
measuring sebum secretion and assessing sebaceous gland activity are also
described. The area of major interest during the last 20 years has
undoubtedly been the mechanisms that control sebaceous gland function. Most
studies have focused on the endocrine control and in particular on the role
of androgens and pituitary hormones, although evidence suggests that
nonendocrine factors may also be important. However, many questions remain
and during the next few years attention will certainly be given to the role
of retinoids and their mode of action in the treatment of acne.</abstract><cop>Bethesda, MD</cop><pub>Am Physiological Soc</pub><pmid>2648418</pmid><doi>10.1152/physrev.1989.69.2.383</doi><tpages>34</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0031-9333 |
| ispartof | Physiological reviews, 1989-04, Vol.69 (2), p.383-416 |
| issn | 0031-9333 1522-1210 |
| language | eng |
| recordid | cdi_proquest_journals_216480077 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Anatomy & physiology Animals Biological and medical sciences Fundamental and applied biological sciences. Psychology Hormones - physiology Humans Lipids - biosynthesis Sebaceous Glands - physiology Sebaceous Glands - secretion Sebum - secretion Vertebrates: skin, associated glands, phaneres, light organs, various exocrine glands (salt gland, uropygial gland...), adipose tissue, connective tissue |
| title | Control and function of sebaceous glands |
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