Absence of lymph nodes in NOD mice treated with Lymphotoxin-[beta] receptor immunoglobulin protects from diabetes

Pregnant nonobese diabetic (NOD) mice were treated with lymphotoxin-[beta] receptor immunoglobulin fusion protein (LT[beta]R-Ig) or control human immunoglobulin on days embryonic day 11 (E11) and E14, and offspring were followed for the development of anti-[beta]-cell antibodies, islet pathology, an...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2004-12, Vol.53 (12), p.3115
Hauptverfasser:	Levisetti, Matteo G, Suri, Anish, Frederick, Katherine, Unanue, Emil R
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Arthritis Autoimmune diseases Care and treatment Dendritic cells Diabetes Diabetes research Immunoglobulins Laboratory animals Lymph nodes Lymphatic system Pathogenesis Proteins
Online-Zugang:	Volltext
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