Glucagon is required for early insulin-positive differentation in the developing mouse pancreas
The embryonic pancreas is thought to develop from pluripotent endodermal cells that give rise to endocrine and exocrine cells. A key guidance mechanism for pancreatic development has previously been found to be epithelial-mesenchymal interaction. Interactions within the epithelium, however, have not...
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Veröffentlicht in: | Diabetes (New York, N.Y.) N.Y.), 2002-11, Vol.51 (11), p.3229 |
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