Molecular dynamics studies of [alpha]-helix stability in fibril-forming peptides

Diseases associated with protein fibril-formation, such as the prion diseases and Alzheimer's disease, are gaining increased attention due to their medical importance and complex origins. Using molecular dynamics (MD) simulations in an aqueous environment, we have studied the stability of the α...

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Veröffentlicht in:	Journal of computer-aided molecular design 2008-01, Vol.22 (1), p.53
Hauptverfasser:	Nordling, Erik, Kallberg, Yvonne, Johansson, Jan, Persson, Bengt
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Biochemistry Biophysics Molecular biology Peptides Prions Proteins
Online-Zugang:	Volltext
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