Insulin inhibits phagocytosis in normal human neutrophils via PKC[alpha]/[beta]-dependent priming of F-actin assembly

Objective: This study investigated the effects of insulin on the phagocytosis of C3bi - and IgG-opsonized yeast particles in normal human neutrophils. Methods: Neutrophils were incubated in different insulin concentrations for 30 minutes and stimulated by C3bi - or IgG-opsonized yeast particles. Pha...

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Veröffentlicht in:Inflammation research 2006-03, Vol.55 (3), p.85
Hauptverfasser: Saiepour, D, Sehlin, J, P. -A. Oldenborg
Format: Artikel
Sprache:eng
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