Blockade of nuclear factor-[kappa]B activation prevents hypodynamic shock and gastric hypoperfusion induced by endotoxin in anesthetized dogs

To investigate whether pyrrolidinone derivative (N2733), an inhibitor of nuclear factor (NF)-kappaB activation, improves altered metabolic and hemodynamic changes and organ dysfunctions caused by endotoxic shock. Prospective, randomized, animal study in a laboratory at a university hospital. Twenty-...

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Veröffentlicht in:	Intensive care medicine 2005-05, Vol.31 (5), p.718
Hauptverfasser:	Mitaka, Chieko, Hirata, Yukio, Narumi, Yutaka, Yokoyama, Kuninori, Makita, Koshi, Katsuyama, Koichi, Imai, Takasuke
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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