Stoichiometry of the cardiac Na(+)/Ca(2+) exchanger NCX1.1 measured in transfected HEK cells

Stoichiometry of the cardiac Na(+)/Ca(2+) exchanger NCX1.1 measured in transfected HEK cells

The stoichiometry with which the Na+/Ca2+ exchanger, NCX1, binds and transports Na+ and Ca2+ has dramatic consequences for ionic homeostasis and cellular function of heart mycocytes and brain neurons, where the exchanger is highly expressed.

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Bibliographische Detailangaben
Veröffentlicht in:Biophysical journal 2002-04, Vol.82 (4), p.1943
Hauptverfasser: Dong, Hui, Dunn, Jeremy, Lytton, Jonathan
Format: Artikel
Sprache:eng
Schlagworte:
Biophysics
Calcium
Cells
Heart
Ions
Sodium
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Zusammenfassung:The stoichiometry with which the Na+/Ca2+ exchanger, NCX1, binds and transports Na+ and Ca2+ has dramatic consequences for ionic homeostasis and cellular function of heart mycocytes and brain neurons, where the exchanger is highly expressed.
ISSN:0006-3495
1542-0086
DOI:10.1016/S0006-3495(02)75543-4